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The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Fungi-produced compounds can change plant root growth.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Blocking JAK-STAT signaling can lead to hair growth.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

People with alopecia areata often have other health issues like skin diseases, metabolic syndrome, stomach infections, lupus, anemia, thyroid problems, mental health issues, vitamin D deficiency, and hearing and eye problems.

Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.