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The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

New compounds may soon be tested to treat excessive hair growth in women.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.

SCD-153 shows promise as an effective topical treatment for alopecia areata.

A compound from Calophyllum inophyllum L. leaf may help treat non-small cell lung cancer.

Dermal Papilla Cells grown in 3D and with stem cells better mimic natural hair growth conditions than cells grown in 2D.

Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.

Minoxidil sulfotransferase is a marker of keratinocyte differentiation and may play a role in hair growth.

Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

PRP may help with aging and osteoarthritis, improving tissue repair and reducing surgery risk.

Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.

Stem cell self-renewal is complex and needs more research for full understanding.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.

Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.

New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Finasteride changes antioxidant enzyme expression, possibly affecting sperm protection in rats.

Blocking prolactin increases the activity of secondary hair follicles in cashmere goats.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.