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Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Humans lost body hair relatively recently in evolution.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Estrogen therapy can reduce skin aging but has cancer risks.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Cathepsin L is essential for normal hair growth and development.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

Telogen effluvium is a common type of hair loss that can resolve on its own or become chronic, with treatment depending on early diagnosis.

Hair loss can significantly affect a person's self-esteem and body image, especially in young people, those who value their looks highly, and women.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Forehead modification greatly increases the perception of femininity and is a safe procedure.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.

Eclipta alba extract may help hair grow similarly to Minoxidil.

Higher doses of cranial irradiation are linked to permanent hair loss.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.