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A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.

Low zinc and selenium levels in sheep are linked to hair loss and thyroid problems.

Finding functions for unknown GPCRs is hard but key for making new drugs.

Premature graying of hair is linked to vitamin D and B12 deficiencies, thyroid issues, iron imbalance, stress, and lifestyle habits, and affects quality of life.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Melatonin affects mouse skin and may regulate skin functions.

Hypothyroidism is often linked to the hair loss condition telogen effluvium.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Key genes and pathways involved in thyroid eye disease were identified, aiding potential treatment and diagnosis.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Biotin treatment can significantly improve hair loss and motor functions in certain metabolic disorders.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

Hormone imbalances from the pituitary, thyroid, and adrenal glands can cause infertility, but treating these disorders can improve fertility.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Testosterone is crucial for development, growth, and various body functions in mammals.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Melasma is a skin condition linked to female hormones, genetics, UV exposure, and certain medications, but not to pituitary, adrenal, or thyroid diseases.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

Hair loss in men and women is linked to high stress hormone levels and other hormonal imbalances, suggesting treatments should be customized to each person's hormones.

Vitamin D receptor helps control hair growth genes in skin cells.

Goat skin changes with the seasons due to genes affected by daylight and hormones.

A woman with Sheehan syndrome improved with hormone treatment.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

SHBG may be a useful early indicator and treatment target for PCOS.