April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that targeting skin-infiltrated memory phenotype T cells could offer a new therapeutic approach to manage lymphopenia-related diseases like graft-versus-host disease and immune reconstitution inflammatory syndrome.
October 2024 in “Journal of the Endocrine Society” This case report discusses a Korean woman who experienced recurrent episodes of painless thyroiditis over 22 years, highlighting the challenges in management due to a lack of established guidelines.
December 2016 in “Journal of evolution of medical and dental sciences” This study reported common skin changes and symptoms associated with thyroid disorders, such as dry skin in hypothyroidism and warm, soft skin in hyperthyroidism, and noted urticaria as a frequent autoimmune association in hypothyroid patients.
2 citations
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May 2018 in “Journal of The American Academy of Dermatology” This study examined 15 female patients with hypothyroidism to investigate the characterization of their alopecia and ruled out other causes, using medical histories, and clinical, trichoscopic, and histologic findings.
April 2019 in “Journal of the Endocrine Society” This case report describes an unusual instance of myxedema in a woman with severe hypothyroidism, presenting with skin findings in atypical locations and improvement following levothyroxine treatment.
April 2019 in “Journal of the Endocrine Society” In this case study, the researchers reported that treating a woman with type B insulin resistance using rituximab, dexamethasone, and cyclophosphamide greatly reduced her insulin needs, but her hyperandrogenic state persisted, suggesting ovarian hyperthecosis.
This abstract provides funding and institutional support information but reports no new research findings.
May 2005 in “Cancer Research” This study found that over-expression of thymosin beta-4 in transgenic mice accelerated wound healing and hair growth, but did not affect tumor progression despite stimulating tumor metastasis.
54 citations
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August 1981 in “British Journal of Dermatology” This study found that patients with alopecia areata had significantly lower T cell numbers and reduced lymphocyte responses compared to healthy controls, correlated with hair loss severity and presence of antithyroid antibodies.
50 citations
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December 2005 in “European Journal of Immunology” This study found that a specific mutation in the mouse RXRalpha gene significantly impacts immune responses and causes hair loss and skin cysts.
December 1951 in “Journal of the American Medical Association” This article reports a case of hair loss and pigmentation changes in a man after using propylthiouracil alongside iodine solution for thyroid and diabetic conditions, providing clinical observations without broader conclusions.
1 citations
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December 2015 in “The Egyptian Journal of Histology” This study found that experimentally induced hypothyroidism in rats is associated with impaired skin structure, but topical application of triiodothyronine (T3) improved these changes to resemble normal skin.
July 2024 in “Journal of Investigative Dermatology” 11 citations
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December 2010 in “American journal of transplantation” This study describes three female islet transplant recipients who unexpectedly developed alopecia areata about 7 years post-transplant, with a possible link to immunosuppressive treatment regimens.
February 2022 in “Journal of Armed Forces Medical College” This case report details a patient with autoimmune hypothyroidism who experienced multiple health issues that improved with comprehensive treatment including Thyroxin replacement and other supportive measures.
64 citations
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May 2000 in “International Journal of Dermatology” This study found that thalidomide increased peripheral lymphocyte counts and reduced inflammation in lupus erythematosus patients, but was associated with polyneuropathy, suggesting careful use in refractory cases.
11 citations
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June 2005 in “Postgraduate Medical Journal” This case report details an instance of transient scrotal hair development in a UK infant, which spontaneously resolved by 7 months of age, with no underlying pathology identified.
8 citations
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January 2009 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This study reports a novel TRbeta gene mutation associated with resistance to thyroid hormone syndrome, which may contribute to various forms of alopecia in the affected family members.
February 2025 in “Revista Eletrônica Acervo Saúde” This report emphasizes the importance of considering thyroid tuberculosis in the differential diagnosis of cervical masses, highlighting the role of biopsy and histopathological examination for accurate diagnosis and treatment.
April 2020 in “Journal of the Endocrine Society” This case report describes a rare and atypical presentation of primary hypothyroidism with myxedema in a two-year-old boy, highlighting the importance of recognizing unusual symptoms for timely treatment.
1 citations
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January 2022 in “Open Journal of Endocrine and Metabolic Diseases” This case report describes a 70-year-old woman with pituitary resistance to thyroid hormone (PRTH) misdiagnosed as Graves disease, highlighting diagnostic challenges in managing this rare disorder.
October 2024 in “Journal of the Endocrine Society” This case report highlights that a patient with resistance to thyroid hormone was misdiagnosed as having Graves’ disease, leading to unnecessary radioactive iodine treatment.
April 2020 in “Journal of the Endocrine Society” In this case report, successful management of a pituitary macroadenoma was achieved with thyroid hormone therapy, leading to reduced tumor size and improvement in symptoms like galactorrhea and headaches.
4 citations
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July 2014 in “Journal of Investigative Dermatology” This study suggests that age-related regenerative decline in hair follicles may be due to an imbalance of signals affecting stem cell activation, with follistatin potentially promoting renewal.
September 2021 in “International journal of Ayurveda and pharma research” In this case report, a patient with subclinical hypothyroidism exhibited a significant reduction in TSH levels after four months of ayurvedic treatment, but levels slightly increased afterward.
December 2019 in “Mehmet Akif Ersoy Üniversitesi Sağlık Bilimleri Enstitüsü dergisi” In this case series, two cats with hypothyroidism and hyperthyroidism achieved clinical remission and normal thyroid function following timely diagnosis and targeted treatment with levothyroxine and methimazole, respectively.
62 citations
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June 2015 in “The Journal of Dermatology” This study found that patients with alopecia areata had higher levels of Th17 cells and lower levels of regulatory T cells compared to healthy controls, suggesting an immune imbalance in these patients.
1 citations
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January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that targeting IL-17 signaling in aged skin reduces inflammation and delays age-related traits, suggesting a potential strategy to prevent age-associated skin ailments.
2 citations
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January 2014 in “Türkiye klinikleri tıp bilimleri dergisi” This study suggests that thyroid autoimmunity may play a role in telogen effluvium pathogenesis, indicating a need for evaluating thyroid autoantibodies in addition to thyroid function tests in these patients.
2 citations
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September 2016 in “Journal of evolution of medical and dental sciences” This study found that patients with thyroid dysfunction were more likely to experience skin disorders such as chronic idiopathic urticaria, vitiligo, and alopecia areata compared to a control group.