Evaluation of Thyroid Autoimmunity in Female Patients with Telogen Effluvium

    January 2014 in “ Türkiye klinikleri tıp bilimleri dergisi ”
    Şule Güngör, İlteriş Oğuz Topal, Gonca Gökdemir
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    TLDR Thyroid autoimmunity may be involved in some female hair loss, suggesting the need to test for thyroid antibodies in these patients.
    In 2014, a study investigated the role of thyroid autoimmunity in Telogen Effluvium (TE), a type of hair loss, in female patients aged 15-49. The study found no significant differences in thyroid-stimulating hormone (TSH), free thyroxine (fT3), or fT4 levels between the TE group and control groups. However, anti-peroxidase (anti-TPO) and anti-thyroglobulin (anti-Tg) levels, which are indicators of thyroid autoimmunity, were significantly higher in the TE group. There was a significant negative correlation between the duration of TE and the fT4 level, and a significant positive correlation between anti-TPO and anti-Tg levels and the duration of TE. The study concluded that thyroid autoimmunity might play a role in the pathogenesis of TE, independent of thyroid functions, suggesting that evaluation of thyroid auto-antibodies is necessary in TE patients, not just thyroid function tests.
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