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Damaging mutations in NFKB2 cause a severe and distinct form of primary immunodeficiency with early-onset and often ACTH-deficiency.

A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.

The scalp's microorganisms significantly affect hair health and disease.

A specific ATR gene mutation is linked to a hereditary oropharyngeal cancer syndrome.

New genetic discoveries may lead to better treatments for alopecia areata.

Notch signaling is essential for healthy skin and hair follicle maintenance.

Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.

Loss of a specific protein in skin cells causes symptoms similar to psoriasis.

RXRα is crucial for proper immune response and links diet to immune function.

Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.

There are two types of stem cells in rodent hair follicles, each with different keratin proteins.

RANKL causes lymph nodes to grow by making certain cells multiply.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

Plet-1 protein helps hair follicle cells move and stick to tissues.

Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

The review suggests that a special cell-derived treatment shows promise for various skin conditions and hair growth but needs more research for confirmation.

Nagashima-type palmoplantar keratosis in Asians is caused by a SERPINB7 gene mutation.

Acne is a temporary skin imbalance during puberty that often resolves on its own.

New treatments for ichthyosis, like protein replacement and gene therapy, show promise and may become standard care.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Certain daily habits like stress, diet, and sleep can affect the severity of hair loss in alopecia areata.

A two-step method was created in 2015 to make more cells that help with hair growth, but they need to be combined with other cells for 4 days to actually form new hair.

Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.

Alopecia areata patients, especially women with nail issues or atopic diseases, are at higher risk for other autoimmune diseases.

A rare gene mutation causes skin fragility and itching without affecting hair or nails.

The KRTAP11-1 gene promoter is crucial for specific expression in sheep wool cortex.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Patients with RASopathies are at risk for autoimmune disorders and should be routinely screened.

Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.