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Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.

Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Cathepsin L is essential for normal hair growth and development.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Skin's Regulatory T cells are crucial for maintaining skin health and could be targeted to treat immune-related skin diseases and cancer.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Thymosin β4 promotes hair growth by activating stem cells in hair follicles.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Mutant mice help researchers understand hair growth and related genetic factors.