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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Blood vessels and specific genes help turn cartilage into bone when bones heal.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Different types of stem cells and their environments are key to skin repair and maintenance.

Fat cells in the skin help start healing and form important repair cells after injury.

A wearable device using electric stimulation can significantly improve hair growth.

MDP hydrogel heals wounds faster and better than other treatments in diabetic mice.

New methods for skin and nerve regeneration can improve healing and feeling after burns.

Mannosylerythritol lipids are good for skin and hair care products.

Smart biomaterials that guide tissue repair are key for future medical treatments.

Minoxidil promotes hair growth but stops working when discontinued.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Platelet-Rich Plasma (PRP) increases the number of new hair follicles and speeds up hair formation.

Apoptosis is crucial for healthy skin and treating skin diseases.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Human liver cells stick to hair protein materials mainly through the liver's asialoglycoprotein receptor.

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

Polyamines help fix DNA damage accurately in cells.

Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.

Skin cell clumping for hair growth is improved by a protein called fibronectin, which helps cells stick and move better.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Peptide hydrogel scaffolds help grow new hair follicles using stem cells.

Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.