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Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Zinc is effective for treating various skin conditions, including warts and acne.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Lichen planus is a skin condition that can resolve on its own, is linked to hepatitis C, and increases the risk of skin cancer.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Transplant success has improved with better immunosuppressive drugs and donor matching.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Children with atopic dermatitis often have sleep problems, affecting their growth and behavior.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Children, especially teenagers, can get severe SARS-CoV infection with symptoms similar to adults, but they typically recover well with supportive care.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.