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TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.

The African spiny mouse can fully regenerate its muscle without scarring, unlike the common house mouse.

Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.

COVID-19 may harm male fertility and damage the reproductive system.

Targeting immune tolerance issues in Alopecia Areata could restore hair growth and maintain remission.

Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.

Retinol may affect immune responses in people with frequent skin boils.

Gray hair can potentially be reversed, leading to new treatments.

People with alopecia areata have higher levels of osteopontin, which might be important in the disease's development, but this doesn't relate to how severe the disease is.

Aged individuals heal wounds less effectively due to specific immune cell issues.

TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Changing how mesenchymal stromal cells are grown can improve their healing abilities.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Animal models have helped understand hair loss from alopecia areata and find new treatments.