19 citations
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August 1996 in “British Journal of Dermatology” This study found that dermal papillae in alopecia areata, including clinically normal follicles, exhibited ultrastructural abnormalities that suggest an early pathological role in the disease's development.
January 1994 in “Nihon Chikusan Gakkaiho” This study observed that mink dermal collagen fibrils undergo structural changes during the hair cycle, with increased fiber thickness and bundle density as minks grow.
November 2024 in “Journal of Investigative Dermatology” Changes in hair follicle structure may help diagnose and monitor alopecia.
24 citations
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January 1969 in “Archives of Dermatological Research” Hair malformations may occur due to timing issues in hair development.
This study identified several age-related changes in gene expression associated with the extracellular matrix of scalp dermal fibroblasts, which may impact hair follicle maintenance in women over 40.
12 citations
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February 2011 in “Zenodo (CERN European Organization for Nuclear Research)” This research describes methods to analyze the mechanical properties and fracture characteristics of hair across different types and ages, using specialized tensile testing and imaging techniques, without reporting new results.
September 2024 in “Skin Research and Technology” This study used atomic force microscopy to identify significant morphological differences in hair from patients with lichen planopilaris compared to healthy controls, noting more scratches, uneven edges, and pitted scales in affected hair, which may aid future research on the condition.
19 citations
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July 2018 in “ACS biomaterials science & engineering” This study showed that chemical and mechanical treatments significantly alter the nanoscale surface properties of hair, affecting its roughness, mechanical stiffness, adhesion, and surface potential.
January 1991 in “Journal of Society of Cosmetic Chemists of Japan” In this study, researchers found that specific enzyme activities in young females' hair follicles were correlated with changes in hair shaft structure and properties, and permanent waving was associated with chemical changes that suggest hair damage.
January 2013 in “Wool textile journal” 2 citations
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April 2019 in “Experimental Dermatology” This study observed that applying a pulling force to hair follicles led to significant compression of nuclei in certain cell layers and distinct collagen changes at different follicle depths.
16 citations
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February 2018 in “Journal of The American Academy of Dermatology” This study found that scalp involvement in dermatomyositis consistently shows a nonscarring pattern with chronic telogen effluvium, featuring telangiectasia and mucin deposition as universal histologic markers.
8 citations
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January 2020 in “PeerJ” This study found significant structural and compositional differences in hair affected by alopecia areata compared to healthy hair, using a range of physico-chemical investigation methods.
13 citations
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February 2019 in “Zoology” Lustre mutant sheep have normal hair structure and proteins but differ in felting properties.
99 citations
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May 1998 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that small proline-rich proteins modify the biomechanical properties of cornified cell envelopes in rodent forestomachs, potentially affecting the tissue's ability to withstand mechanical stress.
6 citations
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January 1967 in “Journal of Small Animal Practice” This study observed that aged dogs exhibit atrophy of the epidermis, appendages, and dermis, along with variable skin changes and increased dermal pigmentation, but lack senile elastosis seen in humans.
19 citations
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July 2009 in “Clinical and Experimental Dermatology” This article discusses how the balding scalp's exposure to UV and near-infrared light may accelerate aging, with changes detectable under ultraviolet light; it presents no new clinical findings.
March 2026 in “International Journal of Health Science” In this narrative literature review, researchers found that physiological skin changes are extremely common during pregnancy due to hormonal and circulatory adaptations, emphasizing the need for healthcare professionals to recognize these changes to provide proper guidance to pregnant women and avoid unnecessary interventions.
7 citations
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March 2020 in “Journal of the American Academy of Dermatology” This study observed that trichoscopic changes associated with EGFRI treatment include pili torti and asymmetric hyperpigmented fusiform widening, along with dermoscopic skin manifestations such as scale and branching vessels.
34 citations
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January 1983 in “Journal of Investigative Dermatology” 1 citations
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September 2015 in “Pathology - Research and Practice” Stress during pregnancy can thin fetal skin.
37 citations
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October 2015 in “PeerJ” This study found that shampoo and conditioner do not alter hair's molecular structure, while perming treatments significantly affect keratin and intermediate filament structures due to bond alterations.
2 citations
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November 2018 in “Veterinary Dermatology” This study found that in poodles, perifollicular changes in the hair follicle glassy membrane are not always linked to calcium deposition.
This study found that, compared to oxidative treatments, reductive perm-waving more severely impacts the intermediate filaments in European human hair, while both treatments alter denaturation kinetics in a first-order manner.
1 citations
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January 2017 in “Indian Journal of Dermatology Venereology and Leprology” This study found that while hair washed with hard water had higher magnesium deposits, it did not show significant structural surface changes compared to hair washed with soft water.
2 citations
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January 2010 This study observed that different hair types on Tianzhu white yaks have similar ultrastructures, but coarse hair fibers show distinct structural differences across body parts.
August 2018 in “Journal of The American Academy of Dermatology” Aging significantly affects the hair and scalp of nonbalding Caucasian women, with changes that differ from male pattern baldness.
1 citations
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April 2017 in “Journal of Investigative Dermatology” This study evaluated the effects of topical glucocorticoids on human skin using non-invasive imaging methods and observed changes such as alterations in skin layer thickness, keratinocyte size, and collagen and elastin signal intensity.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that age-related changes in scalp dermal fibroblasts, including increased MMP-1 and reduced ECM components, may significantly affect the hair follicle environment and contribute to hair aging.
10 citations
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January 2019 in “Skin Research and Technology” In this study, reduced hair density, diameter, and follicle miniaturization were key characteristics of female pattern hair loss in Southern Chinese women, with occipital and temporal sites also affected.