11 citations
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April 2022 in “Biophysical Journal” In this study, certain cysteine residues in Romney sheep wool fibers were labeled more often during stretching tests, particularly under wet conditions, suggesting variability in their disulfide bond contributions to fiber mechanics depending on hydration.
10 citations
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November 2012 in “International Journal of Dermatology” This study identified that certain diseases, including AIDS and systemic lupus erythematosus, may cause African hair to change to a silky, wavy texture similar to neonatal hair in affected patients.
53 citations
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March 2006 in “Biopolymers” This study suggests that increased amounts of less stable disulfide conformers in hair shafts may be linked to the brittleness observed in trichothiodystrophy.
March 2026 in “Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials” This study investigated the mechanical response of the human hair cuticle to strain and found that cuticular deformation directly corresponded with fiber elongation, revealing significant molecular-level changes in disulfide crosslinks but maintained structural stability, highlighting the role of the cuticle in stress resistance.
1 citations
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October 2018 in “Sohag Medical Journal” This study found that pregnant women commonly experience physiological skin changes, such as pigmentary alterations, and are susceptible to various dermatological conditions, including scabies and pregnancy-specific dermatoses.
January 1997 in “Han-guk hyeonmigyeong hakoeji/Applied microscopy” This study observed that the mechanical connection between hair follicles and connective tissue in human fetal scalp skin is weaker than in the corresponding skin components, reflecting dynamic processes in hair growth.
3 citations
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August 2008 in “PubMed” This study found that digital perm treatments using sodium thioglycolate lotion led to the most significant reduction in protein content and greater hair damage compared to other methods and lotions.
April 2023 in “Han'gug miyong haghoeji/Journal of the Korean society of cosmetology” This study compared the effects of direct heat perms and softening heat perms on hair, analyzing damage and morphological changes to understand their impact on hair fibers and provide foundational data for future research.
December 2023 in “International journal of research in dermatology” In this study, physiological skin changes like linea nigra (84.4%) and striae distensae (78.4%) were most common in pregnant women, while pathological changes were shown to be significantly associated with gravida and gestational age.
July 2023 in “Research Square (Research Square)” This study developed finite element models to examine skin's biomechanical properties, finding that structural heterogeneities like Rete ridges and hair follicles create distinct stress and strain patterns that may influence mechanosensation and skin integrity.
February 2019 in “PubMed” This study explores torsional measurements of single hair fibers to differentiate the effects of cosmetic treatments on hair structure, highlighting their potential to reveal shear stiffness changes related to cuticle damage.
October 2024 in “UNESP Institutional Repository (São Paulo State University)” This study investigated the effects of ammonium thioglycolate and amino methylpropanol hair straightening followed by permanent coloring, finding significant physical and chemical changes to both the cuticle and cortex of hair fibers.
This study found that in live mouse epidermal stem cells, chromatin compaction is heterogenous and reflects differentiation status, with transcriptional changes largely preceding chromatin rearrangements during differentiation.
3 citations
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July 2025 in “Acta Biomaterialia” In this study, AFM-based indentation was used to assess mechanical properties of murine skin wounds at two healing stages, revealing that early wounds exhibit stiffer hyperproliferative epithelium compared to granulation tissue, and highlighting significant influences of surface roughness on tissue stiffness measurements.
71 citations
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May 2006 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that trichothiodystrophy hair brittleness is linked to abnormalities in sulfur content and structural organization, making it prone to breakage.
9 citations
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February 2016 in “Anatomical Science International” Hair proteins change location and structure as hair cells mature.
1 citations
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March 2023 in “Anais Brasileiros de Dermatologia”
3 citations
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December 2013 in “Journal of Dermatology” This study found that scanning electron microscopy can identify four specific hair morphology patterns in alopecia areata patients, offering a less invasive diagnostic option compared to punch biopsy.
1 citations
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April 2018 in “Journal of dairy science” This study observed that hair follicle morphology in dairy cows changes during the peripartum period, with fluctuations in hair follicle width and anagen percentage but no overall marked changes in skin morphology parameters.
23 citations
,
March 2023 in “eLife” This study reveals that epidermal stem cell differentiation in mice involves dynamic transcriptional changes, with Keratin-10 transcription preceding gradual chromatin compaction shifts associated with differentiation.
9 citations
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September 2012 in “Journal of Cosmetic Dermatology” This study introduced hair capacitance mapping as a promising technique for assessing hair surface moisture dynamics, revealing that weathered hair loses moisture more quickly than intact hair.
January 2017 in “Durham e-Theses (Durham University)” This study developed new label-free imaging methods to analyze human hair, identifying distinct chemical environments within cuticle layers and changes in hair structure caused by depilatories, while showing that the treatments tested did not significantly affect skin cell differentiation or proliferation.
34 citations
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December 1984 in “Journal of Cutaneous Pathology” This study observed that the thinning and structural abnormalities in monilethrix-affected hair occur at the internodes due to possible periodic dysfunction of the hair matrix, particularly in the cortex.
June 1996 in “Journal of Dermatological Science” Vitamin D3 applied to mouse skin caused more wrinkles and sagging due to changes in the skin's outer layer.
47 citations
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July 1997 in “British Journal of Dermatology” This research observed that during the catagen phase, the inner root sheath of hair follicles becomes an early target, highlighting its potential role in maintaining hair follicle homeostasis.
January 2026 in “Dermatology Practical & Conceptual” This study observed that 78.3% of patients with alopecia areata exhibited nail changes detectable by dermoscopy, notably nail pitting, in contrast to 14.2% of healthy controls, with these changes significantly associated with disease severity, age, and duration.
1 citations
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July 2015 in “Microscopy Research and Technique” In this study, researchers found that patients with Friedreich's ataxia exhibited more pronounced ultra-structural hair alterations compared to carriers, likely due to oxidative stress related to deficient frataxin expression.
May 2015 in “Journal of the American Academy of Dermatology” New hair after alopecia areata can be thinner and change color but usually keeps the same shape.
53 citations
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September 1999 in “Journal of Synchrotron Radiation” This study shows that microdiffraction experiments reveal structural layers in keratinous tissues, each with different keratin types, potentially explaining their dual role as mechanical support and chemical barriers.