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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study aims to understand various diseases in older adults.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Oral antiandrogens effectively treat female hair loss, with better results in higher hair loss grades.

Oestrogens are key for bone growth during puberty in both boys and girls.

Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Medications have become the main treatment for enlarged prostate symptoms, replacing surgery and watchful waiting.

Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.

Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.