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Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Modern hair transplants use small grafts for a natural look and drugs to prevent further loss, with high patient satisfaction.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Melatonin improved mental health and metabolism in women with PCOS.

Intense pulsed light (IPL) is an efficient and safe method for hair removal, reducing hair by about 80%.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Women with PCOS often have mood disorders and a lower quality of life, and treatment should focus on both physical and mental health.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Androgens may block hair growth signals, targeting this could treat hair loss.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Genetics play a role in acne, but how exactly they contribute is not fully understood.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Sex hormones affect brain injury differently in males and females.

Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.

Caffeine applied to the scalp can protect hair follicles from UV damage.

Hair restoration surgery effectively treats hair loss with natural-looking results, using techniques like stem cells and platelet-rich plasma.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.