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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

The Rotterdam Study aims to understand various diseases in older adults.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.

5% minoxidil helps hair regrowth in androgenic alopecia.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Minoxidil and finasteride are effective for male hair loss, minoxidil for female hair loss, and various treatments like corticosteroids work for alopecia areata; treatment should be tailored to the individual.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Some breast cancer chemotherapy can cause permanent hair loss.

Women with PCOS often feel stigmatized and have mood issues, which can lower their sexual satisfaction, but proper treatment and support can help.

Stress can worsen skin conditions by affecting hormone levels and immune response.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.