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This study found that lifestyle interventions improved body composition, hyperandrogenism, and insulin resistance in women with PCOS, but did not affect glucose tolerance, lipid profiles, or clinical reproductive outcomes.

Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.

This review discusses the safety of testosterone therapy for postmenopausal women and concludes that, aside from hirsutism and acne, it appears safe at physiological doses for several years, though more long-term studies are needed.

This case study reports that low-dose testosterone therapy improved libido and sexual functions in a 36-year-old fragile X carrier female with hypoactive sexual desire disorder when monitored regularly for lab parameters.

This study found that a 400-mg dose of oral testosterone with dutasteride increases serum testosterone levels for 8–10 hours in hypogonadal men, with the nanomilled formulation unaffected by food, suggesting a practical twice-daily therapy option.

In this review and meta-analysis, the authors concluded that 5α-reductase inhibitor therapy is not consistently associated with significant increases in serum testosterone levels in men.

This study found that among older men, low levels of free dihydrotestosterone were associated with an increased risk of developing atrial fibrillation.

This case study found that in a male-to-female transgender individual, long-term cyproterone use led to decreased bone mass, which improved with additional oestradiol treatment, highlighting the anabolic role of oestrogens on bone health.

This case report describes a woman with hypertension, alopecia, and other symptoms, revealing that her condition was due to ovarian hyperthecosis, highlighting the overlap of adrenal and ovarian disorders.

In this review, the authors highlight that drugs promoting androgenic activity or inhibiting estrogenic activity may unmask or worsen androgenetic alopecia in genetically predisposed individuals, indicating the need for careful management in clinical settings.

In this study, Brazilian postmenopausal women reported that menopause significantly deteriorates the quality of their skin, nails, and hair, negatively affecting self-esteem and quality of life, with a need for better understanding of hormone replacement therapy's dermatological effects.

This discussion examines the aesthetic symptoms of perimenopause, such as hot flashes and skin changes, and reviews management options like hormone replacement therapy and topical cosmetics, emphasizing the importance of consistency in treatment to maintain results.

This report describes a 27-year-old patient with Ehler-Danlos syndrome who also presented with hypophosphatasia and mastocytosis, and suggests enzyme replacement therapy might alleviate symptoms in such overlapping genetic conditions.

This review discusses the potential roles of androgens and antiandrogens in COVID-19 outcomes, noting unresolved questions about their effectiveness and safety for treatment.

The removal of the adrenal tumor improved the patient's symptoms and reduced androgen levels, indicating successful surgery.

In this narrative review, the authors discuss the potential impact of hormone therapy on androgenetic alopecia among transgender individuals, especially transgender men using testosterone, and its adverse effects on emotional well-being and body image within a socially stigmatized population.

This commentary discusses the feasibility and challenges of uterine transplantation for transgender women, emphasizing anatomical, hormonal, and ethical considerations without reporting new clinical results.

This article reviews the aging process of sebaceous glands, highlighting the role of intrinsic and extrinsic factors on their degradation and reporting no new clinical findings.

This review discusses the impact of HRT on menopausal skin and hair symptoms and argues that potential benefits should be part of informed decision-making for managing menopause.

This case report describes an unusual variant of Turner Syndrome in a 20-year-old female that required comprehensive medical and psychological care, including hormonal therapy that resolved symptoms like alopecia.

This narrative review synthesized current research on hormonal therapies in cosmetic dermatology, finding they offer promising, evidence-based applications for conditions like aging skin, acne, and melasma, but noting that safety and personalized treatment approaches are essential for responsible clinical use.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

In this chapter, the authors discuss how the decline in estrogen during menopause affects skin health, detailing changes like dryness, thinning, and increased sensitivity, and suggest management strategies such as lifestyle adjustments and hormone replacement therapy to address these issues.

This case report highlights the importance of considering pituitary stalk interruption syndrome as a potential diagnosis for patients with short stature, as early detection may allow those affected to achieve normal height.

In this case study, researchers observed a 5.8-year-old male with peripheral precocious puberty due to a germ cell tumor, marked by elevated human chorionic gonadotropin levels. Treatment normalized hormone levels and arrested the puberty progression, highlighting melatonin's potential role in transitions to central precocious puberty.

This consensus document discusses guidelines for gender-affirming hormone therapy in India, offering recommendations based on a review of existing evidence and expert input, without reporting new clinical results.

This article reviews changes in men's sexual health after midlife, exploring physiologic changes, psychological factors, and various treatment options, but it presents no new clinical results.

This study suggests that testosterone therapy in AFAB individuals may modify the methylation of the ESR2 promoter, with changes influenced by factors like total testosterone levels and age.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

This article discusses various potential causes of hair loss in women undergoing renal replacement therapy and emphasizes the importance of thorough patient evaluation, but it reports no new research findings.