research Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP-Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor
Finasteride effectively blocks enzyme causing male pattern baldness.
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research Acne and Systemic Disease
Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
research An Open, Randomized, Comparative Study of Oral Finasteride and 5% Topical Minoxidil in Male Androgenetic Alopecia
Oral finasteride works better than topical minoxidil for hair growth, both are safe.
research The Role of Oral Contraceptives in the Treatment of Hyperandrogenic Disorders
Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.
research 5-Alpha-Reductase Type 2 Deficiency: Is There a Genotype-Phenotype Correlation? A Review
No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.
research Protective Effect of DA-9401 in Finasteride-Induced Apoptosis in Rat Testis: Inositol Requiring Kinase 1 and c-Jun N-Terminal Kinase Pathway
DA-9401 helps protect rat testis from finasteride damage.
research Male Fertility and Skin Diseases
Some skin diseases and their treatments can negatively affect male fertility.
research Diagnosis and Management of Polycystic Ovary Syndrome (PCOS)
The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.
research Prostate-Specific Antigen as a Marker of Hyperandrogenism in Women and Its Implications for Antidoping
PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.
research Bone Density Is Normal in Male Rats Treated with Finasteride
Finasteride doesn't affect bone density in male rats.
research Effects of Exercise Combined with Finasteride on Hormone and Ovarian Function in Polycystic Ovary Syndrome Rats
Exercise and finasteride together improve ovary health in PCOS rats.
research Reversal of Androgenetic Alopecia in a Male: A Spironolactone Effect?
A man's baldness improved possibly due to a medication that blocks male hormones.
research Male-Pattern Hair Loss: A Supraorbital Nerve Entrapment Syndrome?
Hair loss might be due to nerve issues, treatable with electric stimulation or acupuncture.
research Polycystic Ovarian Syndrome: A Pain for Young Women? An Autobiographical Case Study
Early diagnosis and treatment of PCOS can prevent complications and improve symptoms.
research Evaluation of Patients with Polycystic Ovarian Syndrome at a Tertiary Care Center
Obesity greatly affects polycystic ovarian syndrome, and losing weight should be the first treatment for obese patients to improve their chances of ovulation and pregnancy.
research Evaluation of Dry Eye and Meibomian Gland Dysfunction in Female Androgenetic Alopecia Patients
Female hair loss patients more likely to have dry eye and gland issues.
research Pharmacology of Anabolic Steroids
Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
research Fetal Programming of Polycystic Ovary Syndrome by Androgen Excess: Evidence from Experimental, Clinical, and Genetic Association Studies
Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.
research Development of Polycystic Ovary Syndrome: Involvement of Genetic and Environmental Factors
PCOS is caused by both genetics and environmental factors like diet and obesity.
research Probiotic Bacteria Induce a Glow of Health
Probiotic bacteria improved skin and hair health in aged mice.
research Nonalcoholic Fatty Liver Disease and Polycystic Ovary Syndrome
People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.
research Polycystic Ovary Syndrome in Adolescence
PCOS starts in adolescence with hormonal issues, leading to adult health problems, and early treatment is crucial.
research Dermatologic Manifestations of Polycystic Ovary Syndrome
Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.
research Low Sex Hormone-Binding Globulin Is Associated With Low High-Density Lipoprotein Cholesterol And Metabolic Syndrome In Women With Polycystic Ovary Syndrome
Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.
research Role of Oxidative Stress in Polycystic Ovary Syndrome
Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.
research Androgen Action in the Ovary
Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
research Hyperandrogenism in Polycystic Ovarian Syndrome and Role of CYP Gene Variants: A Review
Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.
research Neuroimmunoregulation of Androgens in the Adrenal Gland and the Skin
Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
research Clinical Application of 5α-Reductase Inhibitors
5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.
research Baldness, Acne, and Testicular Germ Cell Tumors
Men with testicular cancer were less likely to experience baldness and severe acne.