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Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

A special blood test helped find the overactive ovary in a teen with PCOS, and removing that ovary improved her condition.

Treatment restored normal sexual characteristics and blood condition in a patient with testicular cancer.

Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.

Testosterone undecanoate safely and effectively increased penis size in male children with 5-alpha-reductase deficiency.

Ovarian vein sampling helped diagnose rare ovarian tumors causing high testosterone, and surgery to remove the tumors lowered the testosterone levels.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

DHT, a testosterone byproduct, causes male pattern baldness.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

The document concludes that careful evaluation is needed to diagnose PCOS correctly due to similar symptoms in other conditions, and accurate testosterone level measurement is crucial.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Mice without the enzyme HSD17B3 still produce normal testosterone, suggesting they have different ways to make it compared to humans.

Phthirusa pyrifolia extract may lower testosterone and harm male rat reproduction without damaging the liver or kidneys.

Testosterone Replacement Therapy can improve sexual health in postmenopausal women with low sexual desire, but more research is needed on its long-term effects.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Testosterone significantly affects urination differences between male and female mice.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

A new gene, JMJD1C, may affect testosterone levels in men.

Androgens play a role in female sexual function, and testosterone therapy can help women with low sexual desire, but more research is needed on treatments and long-term safety.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

Beard cells, unlike scalp cells, produce growth factors in response to testosterone, which may explain differences in hair growth.