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In this study, exposure to the drug finasteride in Silurana tropicalis significantly increased testosterone levels in liver and testis tissues and altered gene expression related to male reproduction and oxidative stress.

This review explores the structural and functional sex differences in mammals beyond reproductive organs, highlighting variations in life expectancy, organ size, metabolism, and immune function, but it reports no new results.

This study found that activation of Wnt/β-catenin signaling in mouse testes promotes spermatogonial differentiation and reduces the stem cell pool, with SHISA6 inhibiting this process and maintaining stem cell characteristics.

This study found that the enhancer of zeste homolog 2 (EZH2) may promote hair growth by increasing STK40 expression and facilitating hair follicle stem cell proliferation and differentiation.

This study found that overexpression of sFRP4 in skin cells reduces Wnt signaling activation, leading to decreased melanocyte differentiation in regenerating hair follicles.

This study reports that in aged mice, hair follicle dermal stem cells exhibit diminished self-renewal and preferential differentiation into dermal sheath cells, contributing to age-related hair loss.

This study observed that a 3D culture model of hair follicle cells showed an anagen-like phase between days 3 to 6 and transitioned to a catagen-like phase by day 7, highlighting cell differentiation and structural development over time.

This study provides detailed taxonomic and pharmacognostic analyses to authenticate and standardize seven herbal medicines, aiding in their differentiation from common adulterants for improved identification and classification.

This review discusses telogen effluvium, a common type of hair loss, focusing on differentiation from other conditions and potential causes, but presents no new research findings.

This study suggests that PrPC plays a role in the differentiation of mouse embryonic stem cells during neurogenesis, impacting neural progenitor cell development.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

This review outlines a systematic method for diagnosing hair loss and presents no new findings; the authors emphasize the importance of biopsy in cicatricial alopecia cases.

This review discusses osteoma cutis, a rare benign condition involving bone formation in the skin, covering its potential origins, diagnostic methods, and treatment options, without presenting new clinical findings.

This research observed that Backhousia citriodora leaf extract effectively reduced sebum production and improved sebum composition across different ethnicities, significantly decreasing skin oiliness and the likelihood of shiny skin when used in a cream applied twice daily for 28 days.

Microfluidic models improve testing for aging, wound healing, and oral tissue, reducing animal testing.

In this study, researchers observed that administering the minimum dose of levothyroxine to a hypothyroid Dalmatian effectively restored normal skin condition and hormonal levels, suggesting levothyroxine's potential effectiveness in managing skin changes caused by hypothyroidism in dogs.

This study found that topical geranium rose oil accelerated hair regrowth and promoted hair follicle elongation in a shaving animal model of C57BL/6 mice.

This study observed increased metallothionein expression in regenerating liver and hyperplastic mouse skin, suggesting a potential role in cellular proliferation and differentiation.

The researchers concluded that their new reconstructed human epidermis model from plucked hair follicle-derived keratinocytes offers a safer and simpler alternative to traditional skin-derived models for studying epidermal function.

In this study, metal-organic frameworks modified with stearic acid were used to deliver cardamonin to hair follicles, significantly promoting hair growth and cell proliferation in testosterone-challenged mice, suggesting potential benefits for androgenic alopecia treatment.

This review discusses the clinical features, genetics, and treatment of 21-hydroxylase deficiency, a common type of congenital adrenal hyperplasia, and reports no new research findings.

This paper reviews the differential diagnoses and diagnostic tests to distinguish alopecia areata from other types of hair loss, without providing new clinical findings.

This study found that dissolving microneedles loaded with platinum nanozymes induced faster hair growth in an androgenetic alopecia model than daily minoxidil applications, with no significant safety concerns.

This review discusses the complexities of diagnosing polycystic ovary syndrome and reports no new results; the authors suggest a thorough and careful diagnostic approach to avoid misdiagnosis and unnecessary tests.

The document concludes that diagnosing and managing plaque psoriasis, particularly in sensitive areas, is challenging and requires careful differentiation from similar skin conditions.

This case report describes a female SLE patient with CNS involvement who developed an acute West Nile virus infection, highlighting the diagnostic challenges in differentiating infection from a disease flare in immunosuppressed individuals.

This review outlines a systematic approach for dermatologists to accurately diagnose hair loss disorders, emphasizing the importance of differentiating between scarring and non-scarring alopecia to guide appropriate treatment decisions.

In this article, the authors detail approaches for diagnosing and managing hyperandrogenism in young women, focusing on conditions like polycystic ovary syndrome and hirsutism, and highlight the importance of differentiating physiological from pathological causes to guide appropriate treatment strategies, often involving combined oral contraceptives.

This chapter reviews the biosynthesis, mechanism of action, and therapeutic effects of testosterone and related androgens, but reports no new research findings.

This review discusses the roles of the transcription factor SOX9 in organ development and maintenance, providing insights into its regulation and diverse functions, but reports no new experimental results.