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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Certain diets can affect skin conditions, but more research is needed to understand these relationships fully.

Treat hair loss with finasteride, minoxidil, or surgery; consider side effects and severity.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.

Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Melatonin solution helps treat hair loss in men and women.

Using steroids can increase the risk of heart problems.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Hormones, nutrition, and seasonal changes regulate hair growth cycles, with androgens extending growth phases and factors like aging and malnutrition affecting hair loss and thinning.

Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.

Topical finasteride and flutamide reduce gland size and enzyme activity, with flutamide being more potent, potentially treating acne, seborrhea, hirsutism, and androgenic alopecia.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

A male with aromatase deficiency improved bone health with estradiol treatment.

A patient with a larger than usual genetic mutation had a broader range of symptoms for a muscle disease.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.