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Finasteride in male rats causes liver and metabolic issues in their offspring.

Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Women with polycystic ovary syndrome tend to have a longer anogenital distance.

Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.

Acne is a chronic skin condition not caused by poor hygiene or diet, and it requires long-term treatment and patient education.

Pumpkin seed oil slightly outperforms minoxidil foam in treating hair loss with fewer side effects.

The document concludes that androgenetic alopecia is common, has a genetic link, and can be diagnosed and treated with medications like finasteride and minoxidil.

Dutasteride does not seem to change rat spermatogenesis or oxidative stress.

Dutasteride did not change rat spermatogenesis or oxidative stress but needs more research.

Testosterone therapy improved physical and social health in a male with 49,XXXXY syndrome.

Removing a testicular tumor in a dog reduced its aggressive behavior and skin problems.

Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Understanding genes and hormones is crucial for managing male puberty and sex development disorders.

Finasteride may effectively treat hair loss in Klinefelter Syndrome patients.

Get head MRI for babies with achondroplasia early, use free immunoglobulin light chains to detect certain neurodevelopmental disorders, and video calls work for speech therapy in patients with facial anomalies.

A male with aromatase deficiency improved bone health with estradiol treatment.

APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Woodhouse-Sakati syndrome often causes sexual development issues, hair loss, learning disabilities, deafness, muscle contractions, limb pain, and diabetes.

Most hair loss in children is caused by a few common conditions, and it's important to diagnose these properly and support the child's mental health.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.

Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.

A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.

Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.