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Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.

A new gene, JMJD1C, may affect testosterone levels in men.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Some drugs can cause hair loss, and stopping these drugs often leads to hair regrowth.

Hair growth is influenced by interactions between skin layers, growth factors, and hormones, but the exact mechanisms are not fully understood.

Genetics and hormones cause hair loss; finasteride treats it safely.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Bcl-2 overexpression protects against UVB damage but worsens hair loss from chemotherapy.

People with late-stage HIV-1 often experience a specific type of hair loss linked to multiple factors, including nutritional issues and immune responses.

Men with Kennedy disease have less chance of hair loss.