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Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Finasteride effectively treats baldness but may cause sexual side effects.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Restoring hair bulb immune privilege is crucial for managing alopecia areata.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Spironolactone most effective for hirsutism, but has side effects.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Some common medications can harm male fertility, but many effects can be reversed.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.