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The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Chemotherapy can cause brain inflammation and damage, and understanding this process could help manage side effects.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Spironolactone and minoxidil together effectively treat female pattern hair loss.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

Finasteride causes lasting fertility decrease in rats.

People undergoing chemotherapy need better support and information to cope with hair loss.

5 alpha-reductase inhibitors can slightly improve symptoms of enlarged prostate but have a high risk of sexual side effects.

Finasteride for hair loss increases risk of long-lasting sexual dysfunction.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Balding hair follicle cells are smaller, grow less well, and need more effort to culture than non-balding cells.

Wait 3 months after COVID-19 before trying assisted reproduction and further research is needed on COVID-19's effects on male hormones and fertility.

Polydeoxyribonucleotide (PDRN) may help lighten skin and treat hyperpigmentation.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.

Genetic counselors should be culturally skilled and aware of transgender patients' unique health risks and needs.

Early medical support for transgender youth is important for their health, with low regret for gender-affirming hormone use and a need for knowledgeable care providers.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Women with female-pattern baldness produce more testosterone, but 5a-reductase inhibition treatment won't help.

Cimetidine did not reduce hair growth in women with hirsutism.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.