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Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Peptide hydrogels heal burn wounds faster and better than standard dressings.

Cathepsin L is essential for normal hair growth and development.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Low fluence photoepilation temporarily removes hair by targeting the hair follicle's pigmented area without severe damage.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Over one-third of women experience hair loss, with female-pattern hair loss being most common, and treatments include minoxidil and possibly hair transplantation.

Trichoscopy can diagnose female hair loss with high accuracy by looking for specific patterns in hair and scalp appearance.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

The document describes how to tell different types of non-scarring hair loss apart by looking at hair and scalp tissue under a microscope.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

A simple screening method found that 6.3% of women in a semiurban area in Sri Lanka have polycystic ovary syndrome, with most showing menstrual irregularities.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Alopecia is a key indicator of thallium poisoning.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Eflornithine cream effectively reduces women's unwanted facial hair but hair returns if treatment stops.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Smoking linked to hair loss in Asian men.

Minoxidil quickly leaves blood, turns into urine metabolites, and has lasting blood pressure-lowering effects.