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Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.

The document concludes that managing skin conditions during pregnancy is important and requires specialized care.

Exposure to the hair loss drug finasteride during pregnancy can cause genital anomalies in male babies, but not in female babies. It's best to avoid this drug in women who could potentially become pregnant.

Corticosteroid therapy for alopecia areata can cause severe hip bone damage.

Rheumatology clinics should always provide preconception counseling for women on DMARDs.

Enriching the French health care database with external data greatly improved its usefulness.

Women experience more side effects and have worse blood pressure control from hypertension treatments than men, despite using different medications.

The consensus provided guidelines for treating the Female Athlete Triad and a system to decide when athletes can return to sports.

Uterine transplants for transgender women are feasible but need more research.

Eating too much selenium can cause bad breath, hair loss, and nail changes, with harmful effects starting at low daily doses.

Low-dose oral minoxidil effectively reduces hair loss in women with female pattern hair loss.

Oral lichen planus is a chronic disease causing mouth discomfort and sometimes needs immunosuppressive treatment.

Hormone therapy in transgender individuals can increase acne and affect hair growth and loss.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

Finasteride and Dutasteride can improve hair growth in male baldness but may cause temporary sexual dysfunction and possibly affect fertility.

PCOS is a condition causing irregular periods, excess male hormones, and infertility, often managed by targeting insulin resistance and specific symptoms.

Accurate diagnosis and timely, tailored treatments improve outcomes in obstetrics and gynecology.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Minoxidil, finasteride, and low-level laser light therapy are effective FDA-approved treatments for hair loss.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

Leflunomide is effective for rheumatoid arthritis but has significant side effects.

Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

Combination of 0.25% finasteride and 3% minoxidil works better than just 3% minoxidil for increasing hair thickness in women.

Some skin conditions are common during pregnancy and can be safely treated without affecting the pregnancy outcome.

Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.

The conclusion is that a thorough approach is needed to diagnose and manage hyperandrogenism in teenage girls, recognizing its major psychological and health effects.