1039 citations,
February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
275 citations,
March 1999 in “Journal of The American Academy of Dermatology” Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.
105 citations,
February 1996 in “Journal of biological chemistry/The Journal of biological chemistry” The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.
100 citations,
April 2010 in “Expert Opinion on Pharmacotherapy” Hair loss in men treated best with early medication or transplant, new treatments researched.
99 citations,
January 2014 in “Nature communications” Scientists created stem cells that can grow hair and skin.
86 citations,
May 2008 in “Cytokine & growth factor reviews” TNF family proteins are crucial for the development of skin features like hair, teeth, and mammary glands.
82 citations,
August 2017 in “Cell Reports” An imbalanced gut and lack of biotin can cause hair loss in mice.
60 citations,
April 2012 in “Physiology” The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
57 citations,
March 2019 in “Immunity” The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
47 citations,
April 2016 in “Lasers in Surgery and Medicine” Low-level laser therapy may improve hair regrowth and thickness for androgenetic alopecia, but more research is needed.
47 citations,
January 2001 in “Journal of Investigative Dermatology” High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.
46 citations,
May 2012 in “Molecular and Cellular Endocrinology” Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
39 citations,
January 2012 in “International Journal of Trichology” Melatonin solution helps treat hair loss in men and women.
29 citations,
January 2019 in “Journal of the European Academy of Dermatology and Venereology” Trichoscopy is useful for diagnosing and monitoring systemic lupus erythematosus, with certain hair and scalp changes indicating more active disease.
25 citations,
September 2006 in “Birth Defects Research” Different processes create patterns in skin and things like hair and feathers.
18 citations,
April 1986 in “International Journal of Cosmetic Science” Minoxidil promotes hair regrowth in early baldness stages and prevents baldness in non-bald scalps.
14 citations,
November 2020 in “International Journal of Molecular Sciences” Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.
11 citations,
May 2021 in “Dermatologic clinics” PRP and cell therapies may help with hair loss, but more research is needed.
4 citations,
August 2011 in “Aktuelle Dermatologie” Topical melatonin is a safe treatment that may reduce hair loss in people with androgenetic alopecia.
3 citations,
May 2014 in “InTech eBooks” Copper deficiency may cause hair loss, and treating it could involve nutrition and hormones.
2 citations,
August 2023 in “Development” Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.
1 citations,
March 2004 in “Journal of The European Academy of Dermatology and Venereology” Hair loss improved with treatment and successful transplant.
December 2023 in “EPRA international journal of multidisciplinary research” Alopecia areata causes sudden hair loss, has genetic links, and can be managed but not cured.
April 2021 in “Journal of Investigative Dermatology” An AI photographic device effectively tracked hair growth improvements in women treated for hair loss.
January 2012 in “Methods in pharmacology and toxicology” TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.
June 2008 in “Springer eBooks” The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."
June 2008 in “British Journal of Dermatology” UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.
October 2007 in “Journal of Investigative Dermatology” The document suggests a bacteria plays a significant role in acne rosacea and that white hair can regain color after transplant, meriting more research on reversing grey hair.
June 2019 in “Brain Imaging and Behavior” Hair loss can indicate brain aging and potential small vessel disease, but more research is needed to understand the clinical impact.
September 1998 in “Journal of The European Academy of Dermatology and Venereology” Phototrichogram helps assess hair loss severity.