8 citations
,
March 2025 in “Developmental Biology” Integumentary organs adapt and evolve for survival, with potential uses in regenerative medicine.
19 citations
,
November 2016 in “Developmental Biology”
2 citations
,
March 2023 in “BMC ecology and evolution” This study suggests that some keratin-associated proteins with antecedents found in non-haired animals may have roles beyond hair characteristics, possibly contributing to the evolution of hair follicles.
68 citations
,
April 2014 in “Journal of Investigative Dermatology” This study identified a new S100 fused-type protein, scaffoldin, in reptiles and birds and suggests that SFTP-positive epithelia serve as scaffolds for the growth of various skin appendages, indicating a common evolutionary origin.
19 citations
,
August 2012 in “Cell death and differentiation” This study found that disrupting the inturned gene in developing mouse epidermis halted hair follicle formation due to impaired keratinocyte differentiation, highlighting primary cilia's role in tissue-specific planar cell polarity signaling.
2 citations
,
August 2020 in “Scientific reports” This study identified genes potentially involved in the development and differentiation of skin appendages in Atelerix albiventris, noting significant enrichment of immune-related genes in hair-type tissues.
December 2014 in “Bangladesh Journal of Veterinary Medicine” In this study, mixed lice infestations and their associated skin changes were observed in the Egyptian lesser blind mole rat, marking the first report of such findings in this species.
11 citations
,
May 1998 in “Acta agriculturæ Scandinavica. Section A, Animal science” This study observed that pelage development in male blue foxes born in early June was more synchronized than those born in early May, with differences likely influenced by melatonin levels.
5 citations
,
November 2010 in “Veterinary Record” Treatment with oral terbinafine and topical enilconazole was successful in resolving a Trichophyton dermatophytosis outbreak in L'Hoest's monkeys, with complete mycological cure achieved after eight weeks.
This research identified genetic sequences that evolved at different rates in hairless versus hairy mammals, suggesting specific genetic changes contributed to the convergent evolution of hairlessness across various mammalian species.
5 citations
,
January 2024 in “Science Advances” In this study, researchers identified Tenascin-C as a marker for touch dome keratinocytes, which maintain themselves and can develop into Merkel cells following injury, showing they share molecular traits with various epidermal keratinocytes.
40 citations
,
December 2012 in “PLoS ONE” This study found that selective deletion of Ctip2 in epidermal keratinocytes in adult mice leads to atopic dermatitis-like inflammation and suggests Ctip2 plays a crucial role in skin barrier maintenance and inflammatory regulation.
21 citations
,
June 2003 in “Journal of Morphology” This study suggests that the epidermis of monotremes and marsupials exhibits a more primitive pattern of protein distribution compared to eutherian mammals, with differences in loricrin distribution and keratinocyte maturation.
April 2023 in “Veterinary world/Veterinary World” This study identified six species of ectoparasitic insects infesting domestic goats in Bulgaria, with Linognathus stenopsis being the most prevalent across the surveyed farms.
November 2023 in “International Journal of Infectious Diseases” In this case study, dermoscopy successfully visualized head lice and their eggs on a 19-year-old girl's scalp, aiding in the diagnosis of pediculosis capitis, which was then treated with sulfur ointment and hair shaving.
8 citations
,
January 2022 in “Current topics in developmental biology/Current Topics in Developmental Biology” December 2022 in “Laboratory Animal Research” This study described two cases of trichoblastomas in the tactile hair skin of aged house musk shrews, highlighting that their histological structure differs from that in humans and other animals.
1 citations
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May 2008 in “Journal of Experimental Biology” This collection of reviews, edited by Ken Lukowiak and Janis Weeks, explores diverse sensory systems across species, including olfaction, echolocation, magnetoreception, and visual adaptations, without presenting new experimental results.
1 citations
,
December 2022 in “Skin Appendage Disorders” This study explores various tests that can be performed during teledermatology visits, such as self-conducted pull tests and ponytail thickness measurements, along with imaging tools, to assess hair loss virtually.
16 citations
,
March 2021 in “EvoDevo” This study found that zebrafish and sticklebacks, despite differences in their tooth regeneration structures, share a similar genetic program during tooth regeneration, suggesting a conserved "successional dental epithelium" in vertebrates.
3 citations
,
June 2020 in “Developmental Cell” This study observed that in chicken skin, large-scale differences in gene expression between feathered and scaly skin are controlled by enhancer-driven uniform expression, while small-scale differences within individual feathers are associated with chromatin looping.
20 citations
,
September 2004 in “Journal of Anatomy” This study suggests that the structure and function of the inner root sheath in mammalian hair may have evolved from simpler forms seen in monotremes, aiding in hair exit without damaging the epidermis.
73 citations
,
January 2016 in “International review of cell and molecular biology” Cornification evolved from keratinization in vertebrates, with differences between mammals and sauropsids.
34 citations
,
January 2004 in “Genomics” In this study, researchers identified a cluster of hair-specific keratin-associated protein genes within the 21q22.3 region, revealing a novel transcription mechanism involving TSPEAR/C21orf29 that may bypass typical transcriptional termination sites.
September 2016 in “Journal of dermatological science” This study identified TSC2 as an important regulator of hair follicle morphogenesis and patterning, with Tsc2cKO mice showing altered hair patterns and frequencies compared to controls.
November 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers mapped gene expression in developing hair follicles to reveal unknown cell populations and markers, suggesting early establishment of cell fates in hair placodes.
6 citations
,
July 2015 in “International Journal of Dermatology” This study observed that multiple familial trichoepitheliomas commonly presented with a cribriform histopathological tumor pattern, differentiating them from solitary trichoepitheliomas.
33 citations
,
June 2007 in “Gene Expression Patterns” This study found that CTIP2 is highly expressed in mouse skin during embryogenesis and adulthood, suggesting it may play a role in skin development and homeostasis.
30 citations
,
June 2013 in “Optometry and vision science” This study reports that a clinical sequence can help eye care practitioners identify Demodex mites, which are often underdiagnosed and undertreated in ocular surface diseases.
January 2024 in “Jurnal Ilmu Kesehatan Hewan” In this case report, a 7-month-old local dog named Oreo was diagnosed with demodicosis and helminthiasis and showed improvement in skin condition after 14 days of treatment with ivermectin, antihistamines, vitamin B complex, fish oil, and sulfur soap.