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research Real-World Experience of Tofacitinib and Baricitinib Use in Alopecia Areata in Greek Population: A Retrospective Analysis With Focus on Safety
This study found that Janus Kinase inhibitors, tofacitinib and baricitinib, showed effectiveness and safety in treating severe alopecia areata in a real-world setting, with optimal tolerability noted in younger individuals.
research Sustainable UV approaches supported by greenness and whiteness assessments for estimating a recently FDA-approved combination for managing urologic disorders: Tukey's test
This study introduces three spectrophotometric techniques for accurately determining finasteride and tadalafil in their combined pharmaceutical form, demonstrating their sustainability, sensitivity, and suitability for quality assurance, alongside a dissolution study following FDA guidelines.
research Use of Excimer Lamp and Topical Tofacitinib 2% Gel in the Treatment of Pediatric Alopecia Areata: A Case Report
This case study reports that a pediatric patient with recalcitrant alopecia areata was treated using a 308 nm excimer lamp and topical tofacitinib 2% gel.
research Telogen Effluvium
This abstract is a poetic narrative that recounts a personal experience involving hair loss, medical examinations, and reflections on life, but it reports no scientific findings or new clinical results.
research Loss of Ten1 in mice induces telomere shortening and models human dyskeratosis congenita
This study found that mice with a homozygous knockout of the Ten1 gene, developed through CRISPR-Cas9-mediated exon 3 deletion, exhibited telomere shortening and symptoms consistent with accelerated aging, such as reduced lifespan, skin changes, aplastic anemia, and cerebellar hypoplasia.
research Tofacitinib treatment in a severe pediatric alopecia areata: A case report and a literature review
This case report found that oral tofacitinib treatment resulted in more than 90% hair regrowth in a 6-year-old with severe alopecia areata, with no relapse after dose reduction.
research The TRF1 telomere protein is essential for the generation and maintenance of iPS cells and marks both pluripotent and adult stem cells
This study found that TRF1 plays a crucial role in maintaining pluripotency and stem cell compartments, but it is not a suitable in vivo telomere length marker.
research Comparison of Efficacy of Oral Tofacitinib Versus Oral Minoxidil in Patients with Alopecia Areata
This study found that oral tofacitinib was significantly more effective than oral minoxidil in reducing disease severity and improving treatment response in patients with alopecia areata over a 12-week period.
research Design of A Stable Microemulsion with Phenolic Compounds from Acanthus ebracteatus for Hair Tonic Applications
This study found that Acanthus ebracteatus extract may promote the proliferation of human hair follicle dermal papilla cells and reported that its microemulsion was stable for 12 weeks.
research The Men’s Training Cup Keep Training: a masturbation aid improves intravaginal ejaculatory latency time and Erection Hardness Score in patients who are unable to delay ejaculation
This study found that the MTCK, a masturbation aid, significantly improved intravaginal ejaculation latency time and some related sexual function scores in men with premature ejaculation after 8 weeks of use.
research Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib.
This study reports significant hair regrowth in 11 patients with severe alopecia areata following longstanding treatment with oral tofacitinib and also highlights successful treatment using topical tofacitinib cream in one case.
research Insights into the regulation of plant plasma membrane H+-ATPase : Interactions with microbial compounds and implications for root hair growth
This thesis reveals that tenuazonic acid inhibits plant plasma membrane H+-ATPase, suggesting its potential as a herbicide due to its impact on root elongation and cell viability in Arabidopsis thaliana.
research Faculty Opinions recommendation of Conditional telomerase induction causes proliferation of hair follicle stem cells.
This study found that induced TERT expression in mouse skin epithelium rapidly transitions hair growth from the resting to active phase by promoting stem cell proliferation through a non-telomere related mechanism.
research Fatal Toxic Epidermal Necrolysis Associated with Minoxidil
Minoxidil can cause deadly skin reaction; monitor patients closely.
research Culprits of Medication-Induced Telogen Effluvium, Part 1
This review covers medication-induced telogen effluvium with a focus on systemic retinoids, antifungal agents, and psychotropic medications, and reports no new clinical results.
research Microneedles as a perspective for transdermal therapeutic systems
This review discusses various types of microneedles and their potential to expand the range of drugs delivered via the skin, but reports no new clinical results.
research BC02 (P80): A systematic review of laser treatment of verrucous epidermal naevi
Laser treatment for skin conditions VEN and ILVEN is effective and liked by patients.
research The Diagnostic Value of Serum Ferritin in Telogen Effluvium
This study found that patients with Telogen Effluvium had significantly higher levels of scalp pain and itching, and serum ferritin levels could effectively differentiate them from healthy controls.
research Development, Optimization, and In Vitro/In Vivo Evaluation of Azelaic Acid Transethosomal Gel for Antidermatophyte Activity
This study found that azelaic acid entrapped in transethosomes exhibited enhanced antidermatophyte activity and improved treatment outcomes in guinea pig models of dermatophytosis compared to free azelaic acid.
research Prevalence and factors associated with telogen effluvium in adult females at Makkah region, Saudi Arabia: A retrospective study
In this study, telogen effluvium was commonly found to be associated with iron-deficiency anemia and hypothyroidism among female patients in Makkah, Saudi Arabia.
research Hair growth induction by the tellurium immunomodulator AS101: association with delayed terminal differentiation of follicular keratinocytes and ras‐dependent up‐regulation of KGF expression
This study reports that AS101 induced hair growth in mice and suggests potential for treating chemotherapy-induced alopecia in humans, which was observed in case report studies with three adolescents.
research Effectiveness of Non-SLS Shampoo Based on VCO and Tectona grandis Leaf Extract for Alopecia Treatment
In this animal study, the researchers reported that a shampoo containing 2.5% teak leaf extract and 0.30% virgin coconut oil significantly increased hair growth rate and reduced hair loss in mice, suggesting potential benefits for addressing hair loss.
research A Mouse Model for the Basal Transcription/DNA Repair Syndrome Trichothiodystrophy
This study found that mimicking the XPD point mutation in mice resulted in trichothiodystrophy-like symptoms, supporting the role of basal transcription and DNA repair defects in the disease.
research Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages
This study suggests that mouse lineage specification during pre-implantation development involves distinct timing and mechanisms for trophectoderm and inner cell mass differentiation, challenging existing models.
research Is tapering and stopping of tofacitinib possible among pediatric and adolescent alopecia areata patients?
This study highlights that alopecia areata, an autoimmune condition often starting in childhood, poses a higher risk of becoming chronic with an early onset and can result in poor therapy response.
research Poster presentationsDP11 Bright, eosinophilic intracytoplasmic inclusion bodies: a rare presentation of acquired epidermodysplasia verruciformis with widespread human papillomavirus infection in a transplant recipient
In this case study, a 46-year-old post-transplant woman with poorly controlled diabetes exhibited a rare acquired form of epidermodysplasia verruciformis associated with HPV-49, marked by unique histological findings that distinguishing it from trichodysplasia spinulosa.
research Mult-trait analysis of GWAS - Perceived youtfulness - UKBB
This study conducted a genome-wide association meta-analysis using UK Biobank data to explore genetic correlations with perceived youthfulness, revealing traits linked to this perception among both male and female participants.
research Relapse of Alopecia Areata Responders After Tofacitinib Withdrawal: A Retrospective Study of 59 Patients
Many patients with alopecia areata relapse after stopping tofacitinib.
research ACUTE TELOGEN EFFLUVIUM: A SEQUELA OF COVID-19 INFECTION
This study found that 74.6% of COVID-19 patients in Prayagraj experienced telogen effluvium hair loss, predominantly affecting females.