Multi-Trait Analysis of GWAS: Perceived Youthfulness in the UK Biobank

    January 2024 in “ Zenodo (CERN European Organization for Nuclear Research) ”
    Nathan Ingold
    Image of study
    TLDR The conclusion is that certain traits, including perceived facial aging and BMI, are linked to how youthful people look, with some differences between males and females.
    This document describes a cross-trait genome-wide association meta-analysis of perceived youthfulness in the UK Biobank (UKBB), divided by sex. The study used Multi-trait Analysis of GWAS (MTAG) software and included traits with a genetic correlation greater than 10% and a P value < 2.3e-5. For females, traits included perceived facial aging, BMI, Vitamin E, C, and Zinc supplement use, age at first period, and contraceptive pill use. For males, traits included perceived facial aging, BMI, cigarettes per day, smoking status, male-pattern baldness, diabetes status, hypertension status, and age at first facial hair. The combined sex analysis included perceived facial aging, BMI, cigarettes per day, smoking status, liking of taking stairs, falls in the last year, use of false teeth, hypertension status, and Vitamin E and Zinc supplement use.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Why do we get bald from evolutionary perspective

      in Chat  213 upvotes 1 month ago
      Baldness is not an evolutionary disadvantage because it occurs after reproductive age. Treatments like Minoxidil and Finasteride are used for androgenetic alopecia but don't address the root cause.

      community Unofficial Dermapen/Roller Guide

      in Treatment  250 upvotes 6 years ago
      Treatments for hair loss, including microneedling (dermarolling and dermapen) and the use of minoxidil, finasteride, and RU58841. It provides detailed information about cost and usage of the various treatments, as well as potential side effects.

      community Embraced baldness. Time to leave this subreddit

      in Chat  873 upvotes 11 months ago
      A user shared their positive experience of embracing baldness after years of trying treatments like Minoxidil and finasteride. They found happiness and confidence by shaving their head, despite some social challenges, and encouraged others to focus on their attitude and seek therapy if needed.

      community 1 month Pyrilutamide. A non responders story to everything.

      in Research/Science  218 upvotes 2 years ago
      My hairline, I am only 23. This conversation is about a user's experience with treatments for androgenic alopecia, including finasteride, dutasteride, RU, minoxidil, progesterone, melatonin, LLLT, oral minoxidil, and Pyrilutamide. They have tried many treatments over the course of two years without seeing much success, and they are considering getting a hair system as a last resort.

      community Rate Cbum hair transplant after 1 year

      in Transplants  440 upvotes 3 weeks ago
      The hair transplant has a straight, unnatural-looking hairline that many find unappealing. The person is not using finasteride or minoxidil, which may affect future hair retention.

      community Hairloss has destroyed my Life completely

      in Chat  339 upvotes 1 month ago
      A young person is distressed about rapid hair loss despite using finasteride and recently starting oral minoxidil. Many suggest continuing treatment, considering dutasteride, and seeking therapy for mental health support.

    Similar Research

    5 / 1000+ results