22 citations
,
May 2003 in “Planta Medica” This study found that torilin from Torilis japonica fruit extract inhibited 5 alpha-reductase in vitro more effectively than alpha-linolenic acid but less effectively than finasteride.
September 2024 in “International Journal of Applied Pharmaceutics” This study describes a new LC-MS/MS method for analyzing Finasteride and Tadalafil, demonstrating system suitability, linearity, and accuracy in pharmacokinetic studies in rats, aligning with USFDA guidelines.
September 2023 in “Journal of the American Academy of Dermatology” This study found that hair care products designed for coily/curly hair are significantly more expensive than those for straight hair, based on pricing data from Amazon.com. This indicates a need for equitable pricing to ensure access to affordable hair care for all hair types.
6 citations
,
May 2022 in “Chemistry & biodiversity” This study identified compounds from Laportea bulbifera with potential inhibitory effects on human steroid 5α-reductase 2, suggesting their application in treating benign prostatic hyperplasia.
January 2024 in “RSC pharmaceutics” This source discusses using stratum corneum ablation as a promising method to enhance transdermal drug delivery by temporarily removing the skin's outermost barrier to improve medication absorption.
14 citations
,
July 2012 in “Journal of the American Academy of Dermatology” This study found that topical tacalcitol improved roughness and scaling in erythromelanosis follicularis faciei et colli, although it was less effective for facial erythema.
3 citations
,
July 2022 in “BMC chemistry” This study introduced and validated new spectrophotometric methods to simultaneously determine finasteride and tadalafil in Entadfi™ capsules with high sensitivity and without interference from excipients.
March 1991 in “Archives of Dermatology” This text is a website user interface and does not include an abstract summary or research findings.
April 2016 in “Journal of Investigative Dermatology” This study found that trametinib and vemurafenib increased sebum production and gene expression related to lipid accumulation in hamster sebocytes, which may help explain certain side effects in patients.
193 citations
,
June 2007 in “The Plant Journal” This study found that the GhDET2 gene plays a crucial role in cotton fiber initiation and elongation, suggesting that modifying brassinosteroid biosynthesis may enhance fiber quality or yield.
April 2023 in “Journal of the American Academy of Dermatology” This study aimed to evaluate the outcomes of switching between two JAK inhibitors, tofacitinib and baricitinib, in treating alopecia areata, due to the lack of data on their comparative efficacy.
December 2015 in “Dermatologic Therapy” This article compares the efficacy of topical tea and zinc sulfate in treating acne rosacea but does not present new clinical results.
2 citations
,
April 2024 in “Cutis” This study reported that despite the limited effectiveness of many current therapies for alopecia areata, patients face substantial financial burdens managing the condition, based on an analysis of ten studies involving approximately 16,000 patients.
29 citations
,
March 2012 in “Journal of Experimental Biology” This study found that ribbed hairs on tarantulas closely resemble chemoreceptors rather than silk-producing spigots, with no silk observed emitting from them under microscopy.
October 2025 in “Biomedicines” This study suggests that Terminalia chebula fruit extract may promote hair growth in androgenetic alopecia by activating specific signaling pathways and inhibiting 5α-reductase, showing effectiveness comparable to finasteride.
1 citations
,
April 2022 in “The Journal of Urology” This study observed that discontinuation rates due to side effects were similar for penicillamine and tiopronin among cystinuria patients, and switching to the alternative agent was beneficial for half of those experiencing issues.
October 2012 in “Sax's Dangerous Properties of Industrial Materials”
7 citations
,
January 2009 in “Journal of Pharmacy Research” This study found that fractions of Tridax procumbens extract demonstrated significant antioxidant activity, comparable to standard ascorbic acid, in laboratory tests.
January 2018 in “Journal of the American Academy of Dermatology” This letter discusses a previous study on tofacitinib for alopecia areata, questioning its statistical analysis and suggesting that steroids may have influenced results, but it reports no new clinical findings.
1 citations
,
January 2023 in “IntechOpen eBooks” This review explores the advantages and drawbacks of the anticancer drug paclitaxel, noting its effectiveness in combination with cisplatin for breast cancer survival, its potential for treating non-cancer conditions, and the mechanisms behind its resistance.
March 2022 in “Oncology Times” In this study, tebentafusp-tebn improved overall survival in patients with metastatic uveal melanoma compared to standard therapies, despite higher rates of significant adverse events.
January 2025 in “International Journal of Mosquito Research” In this study, the combination of petroleum ether extracts from Jacquinia ruscifolia flowers and Thuja orientalis strobili demonstrated synergistic larvicidal effects against third-instar Culex quinquefasciatus larvae, achieving 100% mortality at 250 ppm with noted synergism particularly in a 1:2 ratio.
June 2025 in “British Journal of Dermatology” This study compared oral tofacitinib and methotrexate in treating moderate-to-severe alopecia areata, finding that tofacitinib was more effective at reducing SALT scores and improving scalp hair assessment PRO scores, though both treatments reduced psychological distress similarly without serious adverse effects.
2 citations
,
September 2019 in “South Asian research journal of pharmaceutical sciences” This article reviews the risks of metal exposure from cosmetic products and emphasizes the need for stricter regulation and consumer awareness, without presenting new data or results.
7 citations
,
January 2010 in “JAMA” This abstract highlights that preliminary results from the REDUCE trial indicate dutasteride may lower prostate cancer incidence by 23% in older men compared to a placebo.
13 citations
,
February 2006 in “Analytical Biochemistry” This study reported a simple and validated gas chromatography method to accurately measure finasteride in tablets, showing equivalency to the official method with no significant differences.
12 citations
,
May 2023 in “Molecules” This study identified seven potential enzyme inhibitors from a Polygonum cuspidatum extract using ultrafiltration combined with high-performance liquid chromatography. These compounds showed inhibitory activity against tyrosinase, α-glucosidase, and xanthine oxidase, with most discovered in this extract for the first time.
3 citations
,
January 2010 in “Ghent University Academic Bibliography (Ghent University)” This article reviews the impact of the 2000 revision of the European Patent Convention on drug patent protection and raises concerns about its effects on generic substitution and healthcare professionals.
September 2022 in “PubMed” Entadfi, a mix of finasteride and tadalafil, is used for BPH.