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Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

Mesenchymal stem cell therapy may help treat alopecia areata by promoting hair growth and reducing inflammation.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Skin stem cells can help improve skin repair and regeneration.

MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.

A protein from certain immune cells is key for new hair growth after skin injury in mice.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Androgens prevent hair growth by changing Wnt signals in cells.

Targeting CD200 could be a new treatment for rheumatoid arthritis.

A boy with severe immune deficiency and Epstein-Barr virus died from high-grade B-cell lymphoma.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

Vav2 and Vav3 proteins help control skin stem cell numbers and activity in both healthy and cancerous cells.

Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

Oral cyclosporin doesn't stop hair loss.

Activin A increases inner ear hair cell development, while follistatin decreases it.

Acne patients' skin, both with and without lesions, shows a strong immune response and higher antimicrobial activity.

COVID-19 may cause hair loss and scalp pain due to inflammation and changes in hair follicle receptors, but these symptoms typically resolve in 2 to 4 months.

Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

Some patients with mycosis fungoides or Sézary syndrome experience hair loss, which may be similar to alopecia areata or linked to skin lesions, possibly due to abnormal T cells, and bexarotene can help treat it.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Wnt5a may contribute to psoriasis by reducing skin cell growth, blocking skin cell maturation, and increasing inflammation.

Recombinant keratin materials may better promote skin cell differentiation than natural keratin.

CD4+ skin cells may be precursors to basal cell carcinoma.