research Clinical Investigation of JAK Inhibitor Tofacitinib in Scarring Alopecias
Tofacitinib may slow hair loss in scarring alopecias but is unlikely to regrow significant hair.
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research Small Molecule Inhibitors and Inflammatory Skin Diseases
New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.
research Dickkopf-1 Expression in Androgenetic Alopecia and Alopecia Areata in Male Patients
DKK-1 gene linked to hair loss in AGA and AA patients; more research needed for potential therapy.
research Bioinformatics Analysis of Genes Associated with Patchy-Type Alopecia Areata: CD2 May Be a New Therapeutic Target
CD2 might be a new treatment target for patchy alopecia areata.
research Loss of Langerhans Cells in Scar Lesion of Lichen Planopilaris Is Caused by Downregulation of Integrin αvβ6 in the Epidermal Keratinocytes
Scarred skin in lichen planopilaris loses immune cells due to a decrease in a specific protein in skin cells.
research Lichen Planus and Dyslipidemia: A Systematic Review and Meta-Analysis of Observational Studies
People with lichen planus are more likely to have dyslipidemia, especially higher triglyceride levels.
research Association of Human Beta-Defensin 1 Gene Polymorphisms with Alopecia Areata Patients
Certain gene variations may increase the risk and severity of alopecia areata.
research A Randomized Placebo-Controlled Single-Center Pilot Study of the Safety and Efficacy of Apremilast in Subjects with Moderate-to-Severe Alopecia Areata
Apremilast was not effective in treating moderate-to-severe alopecia areata.
research Recombinant Human Hepatitis B Vaccine Initiating Alopecia Areata: Testing the Hypothesis Using the C3H/HeJ Mouse Model
The hepatitis B vaccine did not cause hair loss in the tested mice.
research Liquid Nitrogen Cryotherapy vs. Betamethasone Lotion in the Management of Alopecia Areata
Liquid nitrogen cryotherapy and betamethasone lotion are equally effective for treating alopecia areata.
research Patchy Alopecia Areata Sparing Gray Hairs: A Case Series
Patchy alopecia areata can affect only pigmented hairs, leaving gray hairs untouched.
research Efficacy and Safety of Topical Corticosteroid Treatment Under Occlusion for Severe Alopecia Areata in Children: A Single-Center Retrospective Analysis
Topical corticosteroids may be a safe and effective treatment for severe alopecia areata in children.
research Alopecia Areata Profiling Shows TH1, TH2, and IL-23 Cytokine Activation Without Parallel TH17/TH22 Skewing
Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
research Retrospective Review of Diphencyprone in the Treatment of Alopecia Areata
Diphencyprone helped most patients with alopecia areata regrow some hair.
research Pharmacological Inhibition of Stearoyl CoA Desaturase in the Skin Induces Atrophy of the Sebaceous Glands
Blocking SCD1 in the skin with XEN103 shrinks sebaceous glands in mice.
research Cutaneous Latanoprost in the Treatment of Alopecia Areata
Applying latanoprost on skin can stimulate hair growth with minimal side effects.
research Comparison of Zinc, Copper, and Iron Content in Hair and Serum in Alopecia Areata Patients with Normal Group
Hair and serum levels of zinc, copper, and iron are similar in people with alopecia areata and healthy individuals.
research The Use of a 1,540 nm Fractional Erbium-Glass Laser in the Treatment of Alopecia Areata
The erbium-glass laser effectively promotes hair regrowth in alopecia areata.
research Update on the Treatment of Alopecia Areata
Some treatments can help hair regrowth in alopecia areata, but none offer a cure, and effectiveness varies.
research Immune Privilege and Alopecia Areata
Restoring immune privilege in hair follicles could help treat certain types of hair loss.
research Clinical and Dermoscopic Patterns of Childhood Alopecia Areata in a Tertiary Care Centre in North India
No link between scalp patterns and alopecia severity in children, but more severe cases often had nail abnormalities.
research Estrogen Induces VEGF Expression in Dermal Papilla Cells
Estrogen increases a growth factor in hair cells which might affect hair loss.
research Assessment of Retinol-Binding Protein 4 in Patients with Alopecia Areata and Androgenetic Alopecia
Higher RBP4 levels found in people with two types of hair loss.
research A Study to Evaluate the Efficacy of Various Topical Treatment Modalities for Alopecia Areata
Steroids are the best treatment for Alopecia Areata with few side effects.
research Gut Microbiota in Alopecia Areata
Alopecia areata may be linked to imbalanced gut bacteria.
research Effect of Topical Gel Administration of Secretome Hypoxia Mesenchymal Stem Cells on IL-10 and TNF-α Gene Expression: An In Vivo Experimental Study in Male Wistar Rats with Fluconazole-Induced Alopecia
SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.
research Efficacy of Janus Kinase Inhibitors in Adult Patients With Alopecia Areata
Janus kinase inhibitors are effective and generally safe for treating hair loss in adults with alopecia areata.
research Non-Ablative Fractional Laser as an Emerging Treatment for Alopecia Areata
Combining corticosteroids and non-ablative fractional laser therapy may effectively treat extensive alopecia areata.
research Oxidative Damage Control in a Human Mini-Organ: Nrf2 Activation Protects Against Oxidative Stress-Induced Hair Growth Inhibition
Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.
research Multiple Sclerosis Disease-Modifying Therapies: Adverse Effect Surveillance and Management
The document concludes that managing side effects of MS therapies is crucial for treatment success and patient adherence.