TLDR Combining corticosteroids and non-ablative fractional laser therapy may effectively treat extensive alopecia areata.
The study reported on two cases of extensive alopecia areata treated with a combination of intralesional corticosteroids and non-ablative fractional laser therapy. Both patients, a 24-year-old female with alopecia totalis and a 59-year-old female with extensive patchy alopecia, showed significant hair regrowth after several treatment sessions. The laser treatment created controlled injuries that stimulated hair regrowth through changes in cytokines and growth factors, rapid epidermal repair, and premature anagen entry. The study concluded that this combination therapy might be a safe and effective treatment for extensive alopecia areata, though further randomized controlled trials are needed to establish optimal protocols.
9 citations,
January 2016 in “Journal of cosmetology & trichology” Fractional laser treatment helped hair regrowth in patients with alopecia areata.
46 citations,
March 2013 in “Journal of Cosmetic and Laser Therapy” Non-ablative and ablative fractional lasers helped hair growth in some cases without major side effects, but didn't work for all hair disorders.
106 citations,
January 2013 in “Clinical and Developmental Immunology” Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.
40 citations,
February 2012 in “Dermatology Online Journal” Lasers might help hair growth in some alopecia cases, but more research is needed to confirm their effectiveness and safety.
50 citations,
December 2010 in “Dermatologic Surgery” Laser treatment can stimulate hair growth for male pattern hair loss.
January 2008 in “The Year book of dermatology” After skin injury, adult mice can grow new hair follicles, and this process can be increased or stopped by manipulating Wnt signals.
January 2021 in “International journal of dermatology, venereology and leprosy sciences” Trichoscopy shows black dots, yellow dots, and empty follicles are common in Alopecia Areata, with broken and exclamation mark hair as typical patterns.
31 citations,
October 2018 in “Journal of the European Academy of Dermatology and Venereology” Trichoscopy effectively diagnoses eyebrow loss, distinguishing between alopecia areata and frontal fibrosing alopecia.
89 citations,
March 2018 in “The Journal of Dermatology” Trichoscopy helps diagnose and monitor alopecia areata by looking at a combination of specific hair and scalp features.
November 2016 in “대한피부과학회지” The document's conclusion cannot be summarized as it is not provided in a language I can understand.