Non-Ablative Fractional Laser as an Emerging Treatment for Alopecia Areata

The study reported on two cases of extensive alopecia areata treated with a combination of intralesional corticosteroids and non-ablative fractional laser therapy. Both patients, a 24-year-old female with alopecia totalis and a 59-year-old female with extensive patchy alopecia, showed significant hair regrowth after several treatment sessions. The laser treatment created controlled injuries that stimulated hair regrowth through changes in cytokines and growth factors, rapid epidermal repair, and premature anagen entry. The study concluded that this combination therapy might be a safe and effective treatment for extensive alopecia areata, though further randomized controlled trials are needed to establish optimal protocols.