January 2013 in “International Journal of Trichology” This case report describes a young girl with trichothiodystrophy and suggests the need for early diagnosis and multidisciplinary interventions for her educational challenges.
16 citations
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June 2009 in “Dermatologic Surgery” This abstract does not contain research results or findings.
April 2017 in “Journal of Investigative Dermatology” In this study, deep phenotyping of 68 patients with XPD gene defects successfully separated individuals by clinical diagnosis and survival status, potentially improving diagnosis and prognosis for xeroderma pigmentosum and trichothiodystrophy.
1 citations
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February 2022 in “Clinical, Cosmetic and Investigational Dermatology” In this study, researchers found that the thyroxine receptor agonist TDM10842 accelerated the onset of anagen, a hair growth phase, in C3H mice, potentially through activation of the Wnt/beta-catenin and Hedgehog pathways, with Pclaf playing a key role in this process.
28 citations
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September 2014 in “Journal of Veterinary Internal Medicine” This study found that the novel drug VDC-1101 showed a 45% objective response rate in treating canine cutaneous T-cell lymphoma, offering a potential treatment option for this challenging disease.
October 2024 in “Journal of the Endocrine Society” In this case report, a 40-year-old woman with systemic lupus erythematosus developed Type B Insulin Resistance Syndrome, characterized by severe hyperglycemia despite high insulin doses, requiring immunosuppressive therapy to manage refractory symptoms.
May 2026 in “Chemical Engineering Journal”
October 2022 in “Hair Transplantation” This article discusses the ergonomic challenges in hair restoration surgeries, particularly FUT and FUE techniques, emphasizing the need to minimize pain and fatigue for patients and surgeons, but it reports no new clinical results.
1 citations
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July 2024 in “Journal of Investigative Dermatology” TAK-279 effectively reduces psoriasis symptoms and is safe.
3 citations
,
August 2022 in “International Journal of Molecular Sciences” This study demonstrated that 5-azacytidine treatment may reduce TSC lesion-related hair follicles in mice, suggesting chromatin remodeling agents could be effective for tuberous sclerosis cutaneous lesions lacking tuberin.
16 citations
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January 2010 in “American Journal of Neuroradiology” This case report describes a 3-year-old boy with trichothiodystrophy, highlighting specific MRI findings of diffuse dysmyelination and osteosclerosis that may be unique to the disorder.
1 citations
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July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this open-label trial, Tofacitinib was well tolerated and improved IFN and cytokine scores, as well as overall skin pathology, in individuals with Down syndrome and immune skin conditions.
October 2022 in “Hair Transplantation” This chapter reviews four innovative devices for follicular unit excision in hair restoration surgery, but it does not report new clinical results or outcomes.
31 citations
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September 1999 in “Molecular Carcinogenesis” This study in a transgenic mouse model found that repressing overexpression of ornithine decarboxylase reduced papilloma development, indicating its role in tumor promotion sensitivity.
September 2019 in “Journal of Investigative Dermatology” This study found that in chronic alopecia areata, increased IL-17 expression and CD8+CD49a-Trm cell infiltration in hair follicles were associated with more severe histopathologic gradings, while Foxp3+mTreg infiltration decreased.
2 citations
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November 2007 in “Hair transplant forum international” This abstract introduces the concept of follicular units (FUs) in the human scalp but presents no new research findings.
2 citations
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June 2025 in “Journal of Investigative Dermatology” CD8+ T cells re-expressing CD45RA may predict treatment resistance in severe alopecia areata.
1 citations
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April 2024 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” In this case report, the authors concluded that cutaneous lupus erythematosus was induced by the PD-1 inhibitor tislelizumab during treatment for metastatic lung adenocarcinoma, despite initial remission and treatment adjustments.
April 2023 in “Journal of Investigative Dermatology” This study suggests that monitoring CD8+ TEMRA cells in patients with rapidly progressive alopecia areata treated with intravenous corticosteroids could help predict therapeutic outcomes.
September 2023 in “Journal of the American Academy of Dermatology” Increased Treg cells and IL-10 may help quick recovery in acute diffuse and total alopecia.
86 citations
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August 2011 in “Toxicological sciences” In this study, researchers found that TCDD exposure accelerated differentiation and altered gene expression in human epidermal cells, indicating the epidermal barrier as a target of TCDD-activated AHR.
77 citations
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January 1980 in “Carcinogenesis” This study found that TPA was significantly more effective than mezerein in inducing dark basal keratinocytes in mouse skin, which may be important in early tumor promotion stages.
17 citations
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May 2011 in “Gene Therapy” This study found that transfecting hair follicle stem cells with a PEI-DNA complex expressing hTERT stimulated hair growth in rats by inducing follicle neogenesis and promoting the anagen phase.
2 citations
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May 2011 in “Hair transplant forum international” This abstract provides no results or study findings; it only includes author affiliations and general commentary.
July 2026 in “Journal of Investigative Dermatology”
15 citations
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January 2013 in “Journal of Cutaneous and Aesthetic Surgery” This study observed that direct hair transplantation, as a modification of follicular unit extraction, was effective in improving baldness in the majority of treated male patients.
145 citations
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May 2008 in “Cancer Science” This review discusses how increased gene copy number for telomerase components may contribute to telomerase up-regulation in cancer cells, although the exact mechanisms are not fully understood.
5 citations
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August 2021 in “Experimental dermatology” This study suggests that Merkel cell polyomavirus T antigen-positive cells resembling Merkel cell carcinoma may originate from epithelial cells in human hair follicles, potentially informing future transgenic mouse models for this cancer.
January 2020 in “Journal of Men s Health” In this study of BPH patients with testosterone deficiency, the combination of TU and dutasteride reduced prostate volume and improved testosterone-related symptoms but was less effective for sexual function compared to TU alone, indicating caution in using dutasteride for those with sexual dysfunction concerns.
12 citations
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March 2013 in “The American journal of dermatopathology/American journal of dermatopathology” This article reports on three new cases of Birt–Hogg–Dubé Syndrome and emphasizes the role of genetic analysis in its diagnosis due to clinical challenges.