87 citations
,
February 2000 in “Journal of Investigative Dermatology” Stem cells in developing hair follicles move to specific areas as they mature.
59 citations
,
September 1994 in “The Journal of Clinical Endocrinology and Metabolism” This study found that 4 weeks of finasteride treatment significantly decreased DHT levels in bald scalp to levels similar to hair-containing scalp in men with male pattern baldness.
29 citations
,
March 2010 in “Cancer epidemiology” This study found that early-onset male pattern baldness was associated with a reduced relative risk of prostate cancer.
7 citations
,
October 2017 in “The Prostate” This study found that male pattern baldness may serve as a clinical marker for circulating sex hormone levels in men with localized prostate cancer, while chest hair density showed no significant hormone association.
6 citations
,
January 2001 in “Dermatologic Surgery” This study observed that female androgenetic alopecia is common among Caucasian women, starting in the late 20s and peaking after age 50.
3 citations
,
December 2020 in “International Journal of Women's Dermatology” Scalp micro-wounding helps promote hair growth in female pattern hair loss.
2 citations
,
April 2016 in “PubMed” This study found that a 12-week regimen of 2% minoxidil combined with a botanical hair solution improved hair growth and patient satisfaction for female pattern hair loss, aiding treatment adherence.
1 citations
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March 1990 in “Clinical Drug Investigation” 2% topical minoxidil can help reduce hair loss and promote hair growth in male pattern baldness.
June 2026 in “Journal of Cosmetic Dermatology” PDRN may help with female hair loss, but more research is needed.
This study developed consensus guidelines for the use of low-dose oral and topical minoxidil in male and female pattern hair loss, recommending specific doses, monitoring procedures, and timing of application around hair transplant surgeries.
This study developed expert consensus guidelines on using low-dose oral and topical minoxidil for pattern hair loss around hair transplant surgery, recommending specific doses, monitoring practices, and timing of use for both male and female patients.
February 2026 in “Expert Opinion on Pharmacotherapy” This study established consensus-based guidelines for using low-dose oral and topical minoxidil in managing pattern hair loss for patients undergoing hair transplant surgery, recommending specific dosages, monitoring procedures, and timing for initiation post-surgery.
July 2023 in “Al-Azhar Assiut Medical Journal” In this study, tinea capitis was identified as the most common cause of noncicatricial alopecia in children, followed by alopecia areata and marginal traction alopecia. Diagnosis using trichoscopy enhanced understanding by revealing specific hair and scalp disorder characteristics.
April 2023 in “Journal of Investigative Dermatology” This study found that autologous cell-based therapy using dermal sheath cup cells showed a moderate increase in hair volume in patients with pattern hair loss, particularly in women.
February 2023 in “Cureus” This study found a significant association between the severity of male pattern baldness and increased levels of depression, loneliness, and internet addiction among male medical students with androgenetic alopecia.
July 2022 in “Journal of Investigative Dermatology” This study suggests that using a non-medicated, hypo-allergenic scalp clarifying shampoo may improve hair volume and reduce shedding in women with lichen planopilaris and female pattern hair loss.
August 2021 in “Journal of The American Academy of Dermatology” This article discusses the androgenicity of progestins used in hormonal contraceptives and its potential impact on female pattern hair loss, but reports no new clinical findings.
April 2021 in “Journal of Investigative Dermatology” This study found that oral spironolactone improved or maintained hair condition in females with scarring alopecia and female pattern hair loss, with 83% of patients tolerating the treatment well, despite some side effects like hyperkalemia and leg cramps.
9 citations
,
January 2001 in “Dermatologic Surgery” This study concluded that female androgenetic alopecia is common among Caucasian women, starting in their late 20s and peaking after age 50.
6 citations
,
December 2013 in “Journal of Cutaneous Pathology” This study found that the distribution of mast cell prostaglandin d-synthase in the scalp spatially aligns with the pattern of androgenetic alopecia, suggesting a programmed vulnerability to hair loss.
4 citations
,
February 2016 in “The Journal of urology/The journal of urology” In this study, the authors observed that treatment patterns for new benign prostatic hyperplasia largely aligned with guidelines, but 5-α reductase inhibitors were used inappropriately based on prostate size as indicated by prostate specific antigen.
August 2004 in “Journal of the American College of Surgeons” This study found that endothelial cells under serum deprivation significantly upregulated genes related to inflammation and coagulation, which may impact outcomes in tissue transfer procedures.
16 citations
,
February 2007 in “Plastic and Reconstructive Surgery” This study found that keratinocytes show increased expression of the TGF-β system and collagen type I with age, suggesting a heightened profibrotic response during skin differentiation associated with scarring.
142 citations
,
August 2015 in “Arthritis & Rheumatology” This study found significant heterogeneity in transcriptome patterns among SSc patients, identifying prominent fibroinflammatory and keratin signatures that may aid in stratifying patients for targeted treatment approaches.
1 citations
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January 2022 in “Journal of Cosmetic Dermatology” This study found that combining oral vitamin D with topical minoxidil improved female pattern hair loss more effectively than either treatment alone.
This study developed consensus guidelines for using low-dose oral and topical minoxidil in patients undergoing hair transplant surgery for pattern hair loss, recommending dosing adjustments, monitoring protocols, and timing for post-surgery application.
January 2023 in “International journal of dermatology, venereology and leprosy sciences” In this study, patients with female pattern hair loss had significantly lower serum levels of vitamin D and ferritin, which could be risk factors for the condition's development.
September 2021 in “Journal of advances in medicine and medical research” This study indicated a correlation between female pattern hair loss and decreased serum levels of Vitamin D3, suggesting that Vitamin D3 evaluation may be important in managing this condition.
In this study, a clear pattern of selective sweep was observed for the SLC24A5 gene, with high linkage disequilibrium and low haplotype diversity, but no clear correlation with UV radiation intensity was found.
34 citations
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February 1993 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study found that 4-MA is a potent inhibitor of testosterone 5α-reductase in human tissues, promising potential for treating androgen-dependent skin conditions like male pattern baldness.