April 2012 in “Informa Healthcare eBooks” Lichen planopilaris is a rare, chronic condition causing hair loss, mainly in middle-aged women, and early treatment is important to prevent permanent baldness.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that JAK1 and JAK3 inhibitors effectively reversed alopecia in a mouse model of AA by reducing skin inflammation, while JAK2 inhibition did not promote hair regrowth.
25 citations
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March 2000 in “Journal of Endocrinological Investigation” Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
8 citations
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January 2002 in “Piel” Postmenopausal women may experience frontal hairline and eyebrow loss due to cicatricial fibrosis.
7 citations
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January 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that epithelial cells in the skin of live mice regulate the density and spatial organization of immune cells, which actively maintain their position despite constant cell turnover.
6 citations
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November 2021 in “Frontiers in immunology” This study suggests that STAT3 signaling in keratinocytes is crucial for maintaining skin homeostasis by regulating hair follicle-specific keratin genes, potentially impacting dermatitis development through microbe-triggered inflammatory responses.
8 citations
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September 1958 in “Acta pathologica et microbiologica Scandinavica” Certain treatments can speed up local hair growth in mice but don't change the overall hair growth pattern.
In this study, researchers analyzed over 5,000 T cells per sample using scRNA+TCR-seq technology and found that dual TCR Tregs are present in high proportions across various mouse tissues, showing unique TCR pairing patterns, V(D)J usage, and mRNA expression compared to single TCR Tregs.
January 1986 in “Journal of Steroid Biochemistry” Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.
July 2023 in “Turkish journal of veterinary research” This study investigated the hair structure of wild pigs in the Balıkesir region using stereomicroscopy and scanning electron microscopy, finding distinct bifurcation patterns, but concluded that pig bristles used in brushes likely wouldn't retain these features, complicating species identification.
research Hair
May 1995 in “Dermatologic Surgery” This article provides contact information for a dermatology department and an international hair restoration society but reports no clinical research results.
October 2013 in “Journal of the American College of Cardiology” Blood pressure that doesn't drop at night is linked to worse blood vessel function in people with high blood pressure.
13 citations
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June 2006 in “Brain Research” Allopregnanolone likely doesn't influence ethanol's rewarding effects in these mice.
This study investigated dual TCR Treg cells in mouse tissues, revealing a high proportion and diverse pairing patterns compared to single TCR Tregs, providing insights into their origins and characteristics across different tissue locations.
168 citations
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December 1986 in “Cancer Chemotherapy and Pharmacology” Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.
2 citations
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March 2012 in “JAMA” Early surgery reduces seizure risk in drug-resistant epilepsy; testosterone to DHT conversion doesn't affect muscle anabolism; veterans with PTSD likely to have riskier opioid use; bevacizumab helps in hereditary bleeding disorder.
This study created a detailed atlas of endogenous peptides across 13 maize tissues during various developmental phases, revealing a complex regulatory network where peptide abundance doesn't always align with their source proteins, signaling unique roles in maize development.
37 citations
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August 2000 in “Journal of Cutaneous Pathology” This study found that keratin immunohistochemistry suggests neoplastic cells in eccrine and apocrine poromas are closely related to dermal sweat duct cells, but cannot differentiate these poromas based solely on keratin patterns.
5 citations
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January 2014 in “International Journal of Trichology” Hair loss on the lower legs is common in middle-aged men, usually harmless, and doesn't need treatment.
January 1953 in “The Lancet” Cortisone may help hair regrow by altering the local environment, with regrowth starting 3-4 weeks after treatment, but its use is not widely recommended.
38 citations
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July 1989 in “Archives of dermatological research” Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
15 citations
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May 2002 in “PubMed” This article explores the hormonal and genetic factors influencing androgenetic alopecia and identifies potential targets for treatment but reports no new clinical findings.
November 2025 in “Stem Cell Research & Therapy” This study suggests that human DSCCs may aid in hair follicle regeneration and reduce microinflammation, with potential applications in regenerative medicine evaluated through a new morphometric analysis.
152 citations
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March 1988 in “Journal of The American Academy of Dermatology” In this study, a unique form of chronic superficial pyoderma gangrenosum with verrucous and ulcerative lesions was reported to heal without systemic corticosteroids in most patients.
24 citations
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March 1987 in “Journal of The American Academy of Dermatology” This study found that 1% and 2% topical minoxidil solutions resulted in clinically noticeable hair growth compared to lower doses or placebo in men with male pattern baldness.
5 citations
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April 2006 in “Skin Research and Technology” This study found that US and EU experts provided similar ratings of hair loss changes from global photographs in male subjects with androgenetic alopecia, supporting the use of standardized photographic evaluations.
4 citations
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January 2019 in “Annals of Dermatology” Higher levels of MiR-92a-1-5p and miR-328-3p found in female hair loss patients.
In this report, a unique case of premature graying in a 32-year-old male, with onset at age 15 and a distinctive fractal pattern, was presented, highlighting the need for further investigation into its potential causes and mechanisms.
November 2025 in “Journal of Investigative Dermatology” Estetrol may help prevent hair loss and support hair growth in women.
89 citations
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January 2001 in “Dermatologic Surgery” Hair loss in women is common, starts in late 20s, and affects 30% of women over 50.