Dissecting the Heterogeneity of Skin Gene Expression Patterns in Systemic Sclerosis

    August 2015 in “ Arthritis & Rheumatology ”
    Shervin Assassi, William R. Swindell, Minghua Wu … Jeffrey T. Chang
    Studysummary This study found significant heterogeneity in transcriptome patterns among SSc patients, identifying prominent fibroinflammatory and keratin signatures that may aid in stratifying patients for targeted treatment approaches.
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    Research cited in this study 3

    1. Defining the Impact of Beta-Catenin/Tcf Transactivation on Epithelial Stem Cells Genes & development · 2005
    2. Transient Activation of Beta-Catenin Signaling in Adult Mouse Epidermis Induces New Hair Follicles, Continuous Activation Maintains Tumors Development · 2004
    3. The Secret Life of the Hair Follicle Trends in genetics · 1992