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GlossaryScleroderma (SSc)

chronic autoimmune disease causing skin and connective tissue hardening

Scleroderma, also known as systemic sclerosis, is a chronic autoimmune disease characterized by the hardening and tightening of the skin and connective tissues. It can affect not only the skin but also internal organs such as the heart, lungs, kidneys, and digestive tract, leading to a range of symptoms from mild to life-threatening. The exact cause is unknown, but it involves an overproduction of collagen, leading to fibrosis and vascular abnormalities.

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research Molecular Genetics of Androgen Insensitivity

January 1995 in “Adolescent and pediatric gynecology”

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Capillaroscopic Patterns in Patients with Systemic Sclerosis, Psoriasis, and Alopecia and Their Correlations with Serum Concentrations of Several Angiogenic Markers

research Capillaroscopic Patterns in Patients with Systemic Sclerosis, Psoriasis, and Alopecia and Their Correlations with Serum Concentrations of Several Angiogenic Markers

March 2015 in “Polish Journal of Public Health”

Blood vessel patterns in skin diseases relate to certain blood markers in systemic sclerosis but not in psoriasis or psoriatic arthritis, and may indicate circulation issues in alopecia.

research Treatment of Scleroderma-Related Microstomia Using Hyaluronic Acid: An Interventional Study

1 citations, November 2023 in “Life”

Hyaluronic acid injections can improve mouth opening and quality of life in scleroderma patients.

A Topical Scalp Serum Containing Adenosine, Magnesium Sulfate, Vitamin C Glucoside, and Pre- and Probiotic Fractions Reduces Discomfort and Associated Symptoms of Sensitive Scalp

research A Topical Scalp Serum Containing Adenosine, Magnesium Sulfate, Vitamin C Glucoside, and Pre- and Probiotic Fractions Reduces Discomfort and Associated Symptoms of Sensitive Scalp

November 2023 in “Dermatologic therapy”

The scalp serum reduced scalp discomfort and symptoms without affecting skin moisture loss.

research Variation In The Ovine Keratin-Associated Protein 15-1 Gene Affects Wool Yield

18 citations, September 2018 in “The Journal of Agricultural Science”

Genetic variation in the KRTAP15-1 gene affects wool yield in sheep.

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community Do you guys wait 24 hours before applying minoxidil after dermarolling [.5 mm]?

sscw in Microneedling 12 upvotes 1 year ago

The conversation discusses whether to wait 24 hours before applying minoxidil after using a .5 mm dermaroller for hair loss treatment. The specific treatments mentioned are microneedling, minoxidil, and dermarolling.

community Something I wish I knew about hairloss 10 years ago

romperstomper291 in Treatment 104 upvotes 2 months ago

Hair transplants can initially yield good results, but native hair is more reliable, and transplanted hair may still be lost over time. Early intervention with treatments like topical finasteride and minoxidil is recommended, but it's important to start with lower doses and manage expectations realistically.