Any treatment not nuking systemic DHT levels? 2/21/2026
Hair loss treatments that avoid significantly lowering systemic DHT levels, focusing on topical options like dutasteride mesotherapy, minoxidil, and ketoconazole. The user is exploring alternatives like KX-826 and RU58841 due to concerns about hormone levels.
View this post in the Community →
Similar Community Posts Join
5 / 5 resultscommunity How to reduce scalp DHT as much as possible?
The conversation discusses reducing scalp DHT to prevent hair loss, with a focus on using dutasteride, finasteride, and other treatments like RU58841 and minoxidil. It highlights the challenges of managing hair loss while on high testosterone levels, suggesting that dutasteride may be more effective than finasteride in such cases.
community 6 Month Update as a Bad Diffuse Thinner
A user shared their 6-month update on hair loss treatment, using daily Dutasteride, oral and topical Minoxidil, Ketoconazole shampoo, topical Finasteride, dermastamping, and PRP treatments. They reported improved hair quality but no significant regrowth or density increase, and plan to continue the regimen for another year before considering a hair transplant.
community Apart from Finasteride, Minoxidil, and Microneedling what are you doing to reverse balding?
Various treatments for hair loss include minoxidil injections, finasteride, dutasteride, microneedling, Nizoral shampoo, and supplements like vitamin D and biotin. Additional methods mentioned are red light therapy, scalp massages, lifestyle changes, and hair transplants.
community Whoever had success with PYRILUTAMIDE, please give us hope outside of 5AR inhibitors.
Users discuss using pyrilutamide for hair loss, seeking alternatives to 5AR inhibitors. They mention using minoxidil, ketoconazole shampoo, and RU58841.
community Losing on Dut 0.5 mg + Minox 2.5 mg daily - end of the road?
A 32-year-old male is experiencing hair loss despite using 0.5 mg Dutasteride and 2.5 mg Minoxidil daily, along with previous hair transplants and Finasteride use. He is considering increasing Dutasteride dosage and exploring other treatments like RU58841, but remains skeptical about their effectiveness and concerned about costs.
Related Research
6 / 6 results
research A decade of progress in androgenetic alopecia management: Emerging therapies and multimodal strategies
This review reports that the treatment of androgenetic alopecia is shifting from single therapies to personalized, multimodal approaches incorporating both traditional and emerging pharmacologics, regenerative strategies, nutraceuticals, cosmeceuticals, and device-based interventions, with combination regimens showing improved outcomes.
research Managing patterned hair loss – a hair raising task!
This review summarizes existing knowledge on diffuse and patterned alopecia, emphasizing recent advancements in treatment beyond FDA-approved options, but it reports no new clinical findings.
research Revisión actualizada del tratamiento de la alopecia androgenética femenina
This review of female androgenetic alopecia treatments reports limited therapeutic options due to unclear pathogenesis, with minoxidil as the only FDA-approved treatment and adjuvant therapies under investigation.
research Androgenetic alopecia; drug safety and therapeutic strategies
This review discusses androgenetic alopecia management with 5α-reductase inhibitors, emphasizing that while dutasteride shows superior efficacy, finasteride is suggested as preferable due to predictable adverse effects and preservation of physiological roles.
research Sulfotransferase SULT1A1 activity in hair follicle, a prognostic marker of response to the minoxidil treatment in patients with androgenetic alopecia: a review
This review discusses the potential of using SULT1A1 expression in the scalp as a biomarker to predict response to minoxidil treatment for androgenetic alopecia, but reports no new clinical results.
research Hormonal Treatment for Skin Androgen-Related Disorders
Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.