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No systemic causes were found for the patients' conditions.

Tinea capitis needs systemic treatment to avoid severe outcomes.

The document concludes that systemic therapy is becoming more important in treating head and neck cancer, with new treatments showing promise.

Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.

Skin lymphoproliferative disorders are hard to diagnose and often linked to systemic diseases, but most have a good prognosis with accurate diagnosis.

Post-finasteride syndrome is rarely linked to sexual and systemic side effects.

The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.

Genetically repaired stem cells may treat certain genetic diseases, Th17 cells are key in fighting systemic fungal infections, hair loss in AGA is due to progenitor cell loss, and α-synuclein transfer might contribute to Parkinson's disease progression.

Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.

The 0.25% finasteride solution, when applied once a day, effectively reduces scalp DHT, potentially minimizing sexual side-effects linked to a systemic DHT reduction.

Cutaneous lymphocytosis in cats is a slowly progressing, relatively benign disease affecting older cats, often causing skin lesions and systemic signs.

RU58841, a nonsteroidal anti-androgen, showed potential as a topical treatment for hair loss, increasing hair density, thickness, and length without systemic side effects in Stumptailed Macaques.

Clascoterone is a new, effective, and safe acne treatment without systemic side effects.

The Polish Society of Dermatology recommends treatments for alopecia areata that vary by severity, including topical and systemic medications, with long-term maintenance important for management.

The woman's skin and hair symptoms were confirmed as frontal fibrosing alopecia, and while facial papules are common in such cases, there's no effective local treatment, but systemic treatments can help.

The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.

Physical exams are important in hair loss diagnosis, considering cosmetic history, systemic diseases, and classifying alopecia types.

Manage vitiligo with treatments, address emotions, and use camouflage techniques.

There is no standardized treatment for hidradenitis suppurativa, and individualized plans are needed.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

Mitochondrial Complex I reduces inflammation and increases bone breakdown by affecting certain immune cells.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Clobetasol propionate ointment can help some people with total hair loss regrow hair.

Cannabinoids may help treat various skin conditions.

Eczema and fungal infections are the most common skin problems in Japan, with different age groups and genders affected by various conditions.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.

Optimizing drug delivery to hair follicles is crucial for effective treatment.