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Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Estrogen therapy can reduce skin aging but has cancer risks.

Too much androgen can cause hair loss; finasteride may help.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.