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    Glossary Synaptic Plasticity

    ability of synapses to change strength based on activity

    Synaptic plasticity refers to the ability of synapses, the connections between neurons in the brain, to strengthen or weaken over time in response to increases or decreases in their activity. This process is fundamental for learning, memory, and overall brain adaptability, as it allows the neural network to reorganize and optimize its function based on experiences and new information.

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    Research 30 of 680

    1. Anxiety-, and Depression-like Behaviour Following Short-Term Finasteride Administration is Associated with Impaired Synaptic Plasticity and Cognitive Behaviour in Male Rats Journal of psychiatric research · 2024
    2. Repeated finasteride administration promotes synaptic plasticity and produces antidepressant‐ and anxiolytic‐like effects in female rats Journal of Neuroscience Research · 2024
    3. Sex-specific Difference of Hippocampal Synaptic Plasticity in Response to Sex Neurosteroids Cerebral cortex · 2019 · 22 citations
    4. Different synaptic stimulation patterns influence the local androgenic and estrogenic neurosteroid availability triggering hippocampal synaptic plasticity in the male rat 2017 · 10 citations
    5. The interaction between finasteride and corticosterone levels: implications for depression-, and anxiety-like behavior and hippocampal synaptic plasticity in male rats Psychopharmacology · 2025
    6. Decision letter for "Repeated finasteride administration promotes synaptic plasticity and produces antidepressant‐ and anxiolytic‐like effects in female rats" 2024
    7. Review for "Repeated finasteride administration promotes synaptic plasticity and produces antidepressant‐ and anxiolytic‐like effects in female rats" 2023
    8. Author response for "Repeated finasteride administration promotes synaptic plasticity and produces antidepressant‐ and anxiolytic‐like effects in female rats" 2023
    9. Decision letter for "Repeated finasteride administration promotes synaptic plasticity and produces antidepressant‐ and anxiolytic‐like effects in female rats" 2023
    10. Review for "Repeated finasteride administration promotes synaptic plasticity and produces antidepressant‐ and anxiolytic‐like effects in female rats" 2023
    11. Review for "Repeated finasteride administration promotes synaptic plasticity and produces antidepressant‐ and anxiolytic‐like effects in female rats" 2023
    12. Synaptic Long-Term Potentiation and Depression in the Rat Medial Vestibular Nuclei Depend on Neural Activation of Estrogenic and Androgenic Signals PLoS ONE · 2013 · 25 citations
    13. Local synthesis and function of neuro-estrogen and neuro-androgen: impact on the hippocampus-related cognition and neuronal plasticity Frontiers in Cellular Neuroscience · 2026
    14. Neurosteroids in Adult Hippocampus of Male and Female Rodents: Biosynthesis and Actions of Sex Steroids Frontiers in endocrinology · 2018 · 61 citations
    15. Bisphenol-A antagonizes the rapidly modulating effect of DHT on spinogenesis and long-term potentiation of hippocampal neurons Chemosphere · 2017 · 10 citations
    16. Pubertal hormones increase hippocampal expression of α4βδ GABAA receptors Neuroscience letters · 2019 · 5 citations
    17. Sex‐dependent responsiveness of hippocampal neurons to sex neurosteroids: A role of Arc/Arg3.1 Journal of neuroendocrinology · 2022 · 3 citations
    18. The Plastic and Functional Changes in Hippocampal Neurons During Pregnancy, Delivery and Postpartum are Reversed by Offspring Deprivation Current psychopharmacology · 2020
    19. Midazolam Inhibits Hippocampal Long-Term Potentiation and Learning through Dual Central and Peripheral Benzodiazepine Receptor Activation and Neurosteroidogenesis Journal of Neuroscience · 2010 · 97 citations
    20. Corticosterone enhances the potency of ethanol against hippocampal long-term potentiation via local neurosteroid synthesis Frontiers in Cellular Neuroscience · 2015 · 11 citations
    21. Neo-synthesis of estrogenic or androgenic neurosteroids determine whether long-term potentiation or depression is induced in hippocampus of male rat Frontiers in Cellular Neuroscience · 2015 · 32 citations
    22. Formononetin: A Pathway to Protect Neurons Frontiers in Integrative Neuroscience · 2022 · 35 citations
    23. Adaptive Balance in Posterior Cerebellum Frontiers in Neurology · 2021 · 21 citations
    24. Locally Synthetized 17-β-Estradiol Reverses Amyloid-β-42-Induced Hippocampal Long-Term Potentiation Deficits International journal of molecular sciences · 2024
    25. Effect of Neurosteroid Withdrawal on Hippocampal GABA‐A Receptor α4‐Subunit Expression in Female Mice The FASEB Journal · 2008
    26. Plasticity of GABAergic Inhibition eScholarship (California Digital Library) · 2014
    27. Finasteride Treatment Inhibits Adult Hippocampal Neurogenesis in Male Mice Pharmacopsychiatry · 2010 · 32 citations
    28. Pericyte Plasticity in the Brain Neuroscience Bulletin · 2018 · 46 citations
    29. Ethanol-induced GABAA receptor alpha4 subunit plasticity involves phosphorylation and neuroactive steroids Molecular and Cellular Neuroscience · 2016 · 11 citations
    30. Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications Toxins · 2022 · 5 citations