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This paper argues that for lupus management, selective immunotherapies like anifrolumab and belimumab, which specifically target parts of the immune system, offer more effective treatment options compared to older, broad immunosuppressive strategies.

In this study involving acne patients, researchers compared the effects of combined fire needle and salicylic acid therapy with conventional treatment, measuring improvements in skin lesion severity, skin barrier function, and microbiota diversity; results are not reported in the abstract.

This study suggests that weekly oral finasteride may be a promising alternative to isotretinoin for treating nodulocystic acne, showing substantial improvements with lower incidence of sexual dysfunction.

This study found that electrospun short fibrous sponges effectively mimic the 3D extracellular matrix, promoting tissue regeneration, angiogenesis, and wound healing in diabetic rats better than 2D fiber membranes.

This retrospective study in pediatric patients with Sjögren's syndrome found consistent indications of tear film instability and identified systemic features like arthralgia, Raynaud's phenomenon, and frequent autoantibody positivity, underscoring the value of integrating clinical and ophthalmological assessments for early diagnosis.

This clinical case report describes a 44-year-old male whose initial diagnosis of rheumatoid arthritis progressed over a decade to include systemic lupus erythematosus and Sjögren's Syndrome, highlighting the complexity of managing multiple autoimmune syndromes.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.

This study found that inhibiting the interaction between HOTAIR and EZH2 can block pro-fibrotic gene expression in fibroblasts and interfere with tissue remodeling in systemic sclerosis patient skin.

This study observed that mice with a whole-body deficiency of Cystathionine-β-synthase developed severe hyperhomocysteinemia and related mild symptoms without increased mortality, indicating HHCy may not directly cause end organ damage.

In this study, dual therapy with tamsulosin and solifenacin significantly improved urinary symptom severity and bladder capacity in BPH patients, but did not alter post-void residual urine volume. This supports using the combination therapy for managing LUTS, especially for storage-related symptoms, in clinical settings.

This study used a mouse model to reveal that S100A4-positive cells, specifically fibroblasts and immune cells, play a crucial role in nipple development, essential for successful lactation, despite no issues with mammary morphology or milk production.

SJS/TEN survivors often have severe, overlooked long-term physical problems that are not properly treated after leaving the hospital.

This study found that EPHA4 and Ephrin A3 genes are differentially expressed during hair follicle development in fine-wool sheep, suggesting roles in follicle regeneration and density.

In vitro, this study found that PTX and HU SF-FA NLCs showed greater cytotoxicity and apoptosis in ovarian cancer cells than pure paclitaxel, suggesting promise as a targeted drug delivery platform.

This study assessed Palestinian women newly diagnosed with breast cancer and found that higher spiritual well-being is associated with improved body image and sexual functioning, and reduced distress from treatment side effects, suggesting spiritual support should be integrated into cancer care.

This study examined data from the FDA Adverse Event Reporting System and found that finasteride use is linked with both known and previously unlisted adverse events, such as erectile dysfunction and post-5α reductase inhibitor syndrome, with variations observed by age and sex.

This study reported that dermoscopy can aid in distinguishing secondary syphilis from other skin conditions by enhancing diagnostic accuracy, though there are no standardized criteria; further research is needed to confirm these findings.

This article introduces signatureSearch, a software package designed for gene expression signature searching and functional enrichment analysis, but reports no new clinical results.

This study found that NFIB and STAT5 work together to regulate mammary-specific genetic programs in mice, with their combined absence hindering functional alveoli formation.

This study found that women with diffuse alopecia exhibited higher anxiety and depression scores compared to controls, suggesting a bidirectional relationship between alopecia and psychological symptoms.

Tofacitinib may effectively treat hair loss and improve symptoms in autoimmune conditions like alopecia areata and Sjögren's syndrome, but long-term treatment might be necessary.

This study observed that the coexistence of Frontal Fibrosing Alopecia and lupus erythematosus in a patient may suggest a shared pathogenic background.

This case report describes a woman with Sheehan's syndrome, leading to severe combined systolic and diastolic heart failure, where treatment improved cardiac function.

This study reports that sildenafil may benefit various dermatological conditions like Raynaud's phenomenon and pressure ulcers, but more research is needed to confirm its efficacy and determine optimal treatment protocols.

In this study, researchers identified two person-centered sexual function profiles among women, linked to physical and psychological factors, with PCOS showing greater, though not significant, presence in the dysfunction profile. The dysfunction was associated with higher adiposity and body-image distress.

This brief report describes a case of Fox-Fordyce disease in a prepubertal girl but reports no new clinical findings.

This case report highlights a successful treatment with granulocyte colony-stimulating factor for cyclic neutropenia in a 16-year-old girl experiencing recurring oral aphthae and fever.

This study reported that a novel nanomedicine combining berberine and sinapic acid significantly inhibited the growth of mouse mammary carcinoma cells and demonstrated an anti-tumor effect in vivo, without significant systemic toxicity after 28 days, suggesting a promising, low-toxicity therapeutic strategy for breast cancer.

This study observed that spiritual well-being significantly correlates with quality of life aspects in newly diagnosed Palestinian women with breast cancer, where factors like inner peace and faith predicted better body image and reduced distress from hair loss.