Fox Fordyce Disease in a Prepubertal Girl

    January 2005 in “ Pediatric Dermatology ”
    Kamaldeep Sandhu, Somesh Gupta, AJ Kanwar
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    TLDR A 10-year-old girl with Fox Fordyce disease improved with treatment, suggesting the disease can occur before puberty and might be underdiagnosed in young girls.
    The document described a rare case of Fox Fordyce disease in a 10-year-old girl, which is unusual given that the condition typically affects women between 13 and 35 years old. The young patient had itchy, hyperpigmented papules in her axillae and suprapubic area for a year. A skin biopsy confirmed the diagnosis, and she experienced some improvement with topical 0.1% adapalene gel treatment over 3 weeks. This case suggests that hormonal factors, which are thought to influence the disease's onset, might not be relevant in all instances, as the disease can also occur in prepubertal girls. The authors propose that Fox Fordyce disease might be underdiagnosed in this younger demographic.
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