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The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

GPR39 is linked to certain cells in the sebaceous gland and helps with skin healing.

Sweat glands and hair follicles are structurally connected within a specific layer of skin fat.

Older people's sweat glands are less effective at helping skin wounds heal due to weaker cell connections.

Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.

The document concludes that proper recognition and treatment of skin appendage disorders are important for management.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Understanding fetal skin development helps diagnose congenital skin diseases.

Apoptosis is essential for human skin development and forming a functional epidermis.

Advanced human skin models improve drug development and could replace animal testing.

Fat cells are important for tissue repair and stem cell support in various body parts.

The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

A disease causing skin issues in young adult German short-haired pointers is hereditary, with most affected dogs not responding to treatment.

VEGFR-2 is active in hair follicles, sebaceous glands, sweat glands, and skin on the human scalp.

Sweat hypersensitivity can cause severe skin issues in horses.

Androgens and other hormones affect hair growth and skin conditions like acne.

Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.

Current methods can't fully recreate skin and its features, and more research is needed for clinical use.

Creating fully functional artificial skin for chronic wounds is still very challenging.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

New markers and pathways have been found in skin tumors, helping better understand and diagnose them.

Botulinum toxin A effectively treated a man's facial cysts with no side effects and lasting results.