research Integrin Signaling Regulates YAP/TAZ to Control Skin Homeostasis
YAP and TAZ are crucial for skin cell growth and repair.
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570-600 / 763 resultsresearch Targeted Overexpression of the Angiogenesis Inhibitor Thrombospondin-1 in the Epidermis of Transgenic Mice Prevents Ultraviolet-B-Induced Angiogenesis and Cutaneous Photo-Damage
Overexpressing thrombospondin-1 in mice skin prevents UVB-induced skin damage.
research Metabolic Syndrome and Skin Diseases
Metabolic Syndrome is linked to several skin conditions, and stem cell therapy might help treat them.
research The Extracellular Matrix Dictates Regional Competence for Tumor Initiation
The extracellular matrix affects where tumors can start in the body.
research PPAR-γ Signaling as a Key Mediator of Human Hair Follicle Physiology and Pathology
PPAR-γ is important for healthy hair and its problems, and more research on PPAR-γ treatments is needed.
research Impaired Hair Growth and Wound Healing in Mice Lacking Thyroid Hormone Receptors
Thyroid hormone receptors are essential for hair growth and wound healing.
research Genetically Modified Laboratory Mice with Sebaceous Glands Abnormalities
Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
research Cellular and Metabolic Basis for the Ichthyotic Phenotype in NIPAL4 (Ichthyin)–Deficient Canines
Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.
research Epithelial Expression of the Hormone Leptin by Bovine Skin
Cattle skin has leptin which might control skin and hair growth.
research Elevated Ornithine Decarboxylase Activity Promotes Skin Tumorigenesis by Stimulating the Recruitment of Bulge Stem Cells but Not via Toxic Polyamine Catabolic Metabolites
Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
research The Importance of Basonuclin 2 in Adult Mice and Its Relation to Basonuclin 1
Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.
research Transcriptional Regulation of the Thymus Master Regulator Foxn1
Foxn1 gene regulation is crucial for thymus development but not for hair growth.
research Steatocystoma Multiplex
Steatocystoma multiplex causes recurring skin cysts and needs early recognition for better management.
research Molecular and Cellular Characterization of Avian Reticulate Scales and the Evolutionary Development of Skin Appendages in Foot Soles
Bird foot scales develop differently and can repair but not fully regenerate due to the lack of specialized stem cell areas.
research Acne Syndromes and Mosaicism
Understanding how acne develops in different diseases could lead to new treatments.
research The Role of Linoleic Acid in Skin and Hair Health: A Review
Linoleic acid is important for healthy skin and hair.
research Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
research Data from Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened
The treatment was ineffective in humans.
research Patched-Associated Tumors: Modifier Genes and Pathogenesis
The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
research Biology of the Skin and Dermatological Disease
Knowing how skin works and its diseases helps doctors diagnose and treat skin conditions better.
research Skin Structure
Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
research Ichthyosis
The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.
research Stem Cell Dynamics in the Hair Follicle Niche
Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
research Expression Patterns of Hair-Related Keratins and Epithelial Keratins in Onychopapilloma: The Significance of Clarifying the Origin of Onychopapilloma
Onychopapilloma likely originates from the nail bed, not the nail matrix.
research Cytochrome P450: A Target for Drug Development for Skin Diseases
Modulating Cytochrome P450 activity could help develop new skin disease treatments.
research DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization
Vitamin D receptor is important for regulating hair growth and wound healing in mice.
research Surgical Treatment of the Brow and Upper Eyelid
Individualized assessment and meticulous planning are crucial for successful brow and upper eyelid surgery.
research Update on the Genetics of Androgenetic Alopecia, Female Pattern Hair Loss, and Alopecia Areata: Implications for Molecular Diagnostic Testing
Genetic factors affect hair loss, and molecular testing may help predict, diagnose, and treat it.
research Plastic Surgical Considerations in Pediatric Dermatologic Abnormalities
Treat pediatric skin issues with accurate diagnosis, multidisciplinary team, and various treatment options.
research Heterogeneity of Ornithine Decarboxylase Expression in 12-O-Tetradecanoylphorbol-13-Acetate-Treated Mouse Skin and in Epidermal Tumors
ODC expression in mouse skin and tumors is varied and can be inhibited by retinoic acid or cycloheximide.