research Biology of the Skin and Dermatological Disease
Knowing how skin works and its diseases helps doctors diagnose and treat skin conditions better.
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research Skin Structure
Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
research Ichthyosis
The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.
research Stem Cell Dynamics in the Hair Follicle Niche
Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.
research Cytochrome P450: A Target for Drug Development for Skin Diseases
Modulating Cytochrome P450 activity could help develop new skin disease treatments.
research DNA Damage-Inducible Transcript 4 Is an Innate Surveillant of Hair Follicular Stress in Vitamin D Receptor Knockout Mice and a Regulator of Wound Re-Epithelialization
Vitamin D receptor is important for regulating hair growth and wound healing in mice.
research Surgical Treatment of the Brow and Upper Eyelid
Individualized assessment and meticulous planning are crucial for successful brow and upper eyelid surgery.
research Update on the Genetics of Androgenetic Alopecia, Female Pattern Hair Loss, and Alopecia Areata: Implications for Molecular Diagnostic Testing
Genetic factors affect hair loss, and molecular testing may help predict, diagnose, and treat it.
research Plastic Surgical Considerations in Pediatric Dermatologic Abnormalities
Treat pediatric skin issues with accurate diagnosis, multidisciplinary team, and various treatment options.
research Heterogeneity of Ornithine Decarboxylase Expression in 12-O-Tetradecanoylphorbol-13-Acetate-Treated Mouse Skin and in Epidermal Tumors
ODC expression in mouse skin and tumors is varied and can be inhibited by retinoic acid or cycloheximide.
research Genetic Dissection of Retinoic Acid Function in Epidermis Physiology
Retinoic acid affects skin and hair health by working with specific receptors, and its absence can lead to hair loss and skin changes.
research ASH2L Mediates Epidermal Differentiation and Hair Follicle Morphogenesis via H3K4me3 Modification
ASH2L is essential for skin and hair development.
research Expression of Mu-Opiate Receptor in Human Epidermis and Keratinocytes
μ-opiate receptors in skin cells may affect skin health and healing.
research Acyl-CoA Binding Protein and Epidermal Barrier Function
ACBP is essential for healthy skin and fur by maintaining the skin's barrier function.
research Alopecia Areata in a Renal Transplant Recipient on Cyclosporin
A kidney transplant patient on cyclosporin experienced unexpected severe hair loss, which improved with treatment adjustments.
research Deciphering the Role of the Hexosamine Pathway in Skin Homeostasis
The hexosamine pathway helps protect skin cells from stress and may improve skin and hair health.
research An Ovol2-Zeb1 Transcriptional Circuit Regulates Epithelial Directional Migration and Proliferation
The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
research Development, Formulation, and Characterization of an Adapalene-Loaded Solid Lipid Microparticle Dispersion for Follicular Penetration
Researchers created a skin treatment that could effectively deliver medication into hair follicles.
research Leptin Controls Hair Follicle Cycling
Leptin helps start the growth phase of hair.
research Clinical and Microscopic Features of Generalized Discoid Lupus Erythematosus in Dogs (10 Cases)
Dogs with generalized discoid lupus erythematosus have similar symptoms to humans and need continuous treatment.
research The Notch Intracellular Domain Has an RBPj-Independent Role During Mouse Hair Follicular Development
The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.
research Trichoscopy: A Useful Tool in the Preliminary Differential Diagnosis of Autoimmune Bullous Diseases
Trichoscopy helps quickly identify autoimmune diseases on the scalp but should be used with other standard tests.
research Hair Loss in Autoimmune Cutaneous Bullous Disorders
Hair loss in autoimmune blistering skin diseases varies and may regrow with disease control.
research Pseudo Pemphigus Phenotypes in Mice with Inactivated Desmoglein 3
Mice with a mutated Dsg3 gene showed severe symptoms but not the typical blistering of pemphigus vulgaris.
research Reduced Levels of Serum 25-Hydroxyvitamin D in Alopecia Areata: A Systematic Review and Meta-Analysis
People with alopecia areata often have lower vitamin D levels than healthy people.
research Reply
Minoxidil solution used on the scalp did not lower blood pressure in patients without hypertension.
research Anti-Basal Cell Carcinoma Efficacy of a Topical Hedgehog Inhibitor Without Adverse Effects in Gorlin Syndrome Patients in a Phase 2 Randomized Controlled Trial
Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.
research Vitamin D and Skin: A Review and Update
Vitamin D is important for skin health and can help treat and prevent various skin conditions.
research Dysfunction of Hair Follicle Mesenchymal Progenitors Is Associated with Age-Related Hair Loss
Age-related hair loss is linked to the decline and dysfunction of hair follicle stem cells.
research Cornification
Cornification is the process where living skin cells die to create a protective barrier, and problems with it can cause skin diseases.