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Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Finasteride may help reduce symptoms in male Tourette syndrome patients.

Blocking CRF-R1 can reduce alcohol intake in stressed mice.

Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.

The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.

Eating glucoraphanin can help prevent psychosis in offspring whose mothers had immune system activation.

Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

People with Seasonal Affective Disorder have different brain activity in certain areas when resting.

The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.

The research suggests that Tourette syndrome is linked to both brain signaling and immune system pathways.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Autoimmune liver diseases are likely linked to certain skin conditions like vitiligo and psoriasis.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

Gilles de la Tourette syndrome is treatable, with behavioral therapy as a recommended first option and other treatments available for more severe cases.

Finasteride can cause sexual problems and depression in young men.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.

Finasteride significantly reduced tics and obsessive-compulsive symptoms in patients with Tourette syndrome.

Finasteride improved symptoms in a schizophrenia patient.

Isoallopregnanolone may be a safe and effective treatment for reducing tics in a mouse model of Tourette syndrome.

Finasteride reduces movement issues in Parkinson's disease rats.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.