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The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Targeted cancer therapies often cause serious skin problems that need careful management.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Aging causes skin stem cells to work less effectively.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Eating disorders like anorexia and bulimia cause skin problems, and dermatologists can help detect these disorders early for better treatment outcomes.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that certain genetic mutations and dietary factors are involved in acne development, and treatments like isotretinoin and diet changes can help manage it.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

New antifungal treatments for a children's scalp infection are effective and safe, but it's not decided if they will become the preferred option over the old treatment.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.